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(Stroke. 2008;39:3421.)
© 2008 American Heart Association, Inc.
Research Letters |
From the Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Correspondence to Terence J. Quinn, MRCP, Gardiner Institute of Cardiovascular and Medical Sciences, University of Glasgow, Western Infirmary, Church Street, Glasgow G11 6NT, UK. E-mail Tjq1t{at}clinmed.gla.ac.uk
Background and Purpose— Modified Rankin score (mRS) is traditionally graded using a face-to-face or telephone interview. Certain stroke assessment scales can be derived from a review of a patients case-record alone. We hypothesized that mRS could be successfully derived from the narrative within patient case-records.
Methods— Sequential patients attending our cerebrovascular outpatient clinic were included. Two independent, blinded clinicians, trained in mRS, assessed case-records to derive mRS. They scored "certainty" of their grading on a 5-point Likert scale. Agreement between derived and traditional face-to-face mRS was calculated using attribute agreement analysis.
Results— Fifty patients with a range of disabilities were included. Case-record appraisers were poor at deriving mRS (k=0.34 against standard). Derived mRS grades showed poor agreement between observers (k=0.33). There was no relationship between certainty of derived mRS and proportion of correct grades (P=0.727).
Conclusion— Accurate mRS cannot be derived from standard hospital records. Direct mRS interview is still required for clinical trials.
Key Words: clinical trials drug trials methodology outcomes randomized, controlled trials scales therapy treatment
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