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(Stroke. 1973;4:547.)
© 1973 American Heart Association, Inc.

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Dexamethasone as Treatment in Cerebrovascular Disease. 2. A Controlled Study in Acute Cerebral Infarction

RAYMOND B. BAUER M.D.¹ HENRY TELLEZ M.D.¹

¹ Department of Neurology, Wayne State University School of Medicine, 3825 Brush Street, Detroit, Michigan 48201

Fifty-four patients with acute cerebral infarction were included in a double-blind study to evaluate Decadron® as therapy. When comparison of patients with similar levels of consciousness was made, there was no significant difference between those patients receiving Decadron® and those receiving placebo therapy.

Three patients developed gastrointestinal tract bleeding in the placebo group, but there were none in the Decadron®-treated group.

There was no good correlation between the clinical state of the patient and the CSF pressure, either on admission or during the 14-day course of the study.

Key Words: CSF pressures in cerebral Infarction • Gl bleeding with use of steroids • effect of steroids on CSF pressure

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