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(Stroke. 1974;5:725.)
© 1974 American Heart Association, Inc.

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Neurovascular Complications of Dialysis and Transplantation

LCDR ROBERT D. HARRIS MC USN¹; J. KEITH CAMPBELL M.D.²; FRANK M. HOWARD M.D.²; JOHN E. WOODS M.D.²; CARL F. ANDERSON M.D.²; GEORGE P. SAYRE M.D.²

¹ Department of Neurosurgery, University of Minnesota, Minneapolis, Minnesota
² Departments of Neurology, Surgery, and Pathology and Anatomy, and the Division of Nephrology and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55901

Dialysis and transplantation are now standard treatments for end-stage renal failure. Often, neurologists are consulted regarding the neurological complications of these therapeutic procedures. In addition to previously reported complications, neurovascular disease is being recognized as a cause of mortality and morbidity in these patients. We report two cases of apparent thromboembolic stroke in young patients with renal failure -- one treated by dialysis and the other by renal transplantation. The risk factors of both dialysis and transplant are identified and data from the American College of Surgeons/National Institutes of Health Transplant Registry are reviewed.

Key Words: cerebrovascular accident • risk factors • vasculitis • accelerated atherosclerosis • subdural hematoma • steroid lipemia • subarachnoid hemorrhage • diabetic lipemia • hypercoagulability • uremic lipemia