This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by GERTZ, S. D. Articles by NELSON, E. Search for Related Content PubMed PubMed Citation Articles by GERTZ, S. D. Articles by NELSON, E.

(Stroke. 1975;6:357.)
© 1975 American Heart Association, Inc.

---

Endothelial Cell Ischemic Injury: Protective Effect of Heparin or Aspirin Assessed by Scanning Electron Microscopy

S. DAVID GERTZ PH.D.¹; MARSHALL L. RENNELS PH.D.¹; ERLAND NELSON M.D., PH.D.¹

¹ Departments of Neurology and Anatomy, University of Maryland School of Medicine Baltimore, Maryland 21201

Scanning electron microscopic observations of the luminal surface of the rabbit common carotid artery subjected to occlusion for 30 minutes or two hours revealed crater-like and balloon-like defects in the endothelial surface. The frequency of occurrence of these abnormalities was significantly decreased by pretreatment with heparin or aspirin in doses considered to have antiplatelet aggregating activity.

Key Words: anticoagulants • carotid artery • vascular pathology

This article has been cited by other articles:

				T. Stefanec Circulating Apoptotic Endothelial Cells Blood, August 15, 1999; 94(4): 1482 - 1483. [Full Text] [PDF]

				R. K. Laha, M. Dujovny, and M. Dujovny Antiplatelet Agents in Microvascular Surgery Vascular and Endovascular Surgery, January 1, 1980; 14(1): 39 - 48. [PDF]