Stroke, Vol 7, 83-88, Copyright © 1976 by American Heart Association
RR Myers and M Intaglietta
Arteriolar diameters and venular erythrocyte velocities in the small pial
vessels on the surface of the cat brain were measured by TV methods during
induced epileptic seizures through a cranial window. Grand mal seizures
maximally dilated arterioles and increased venular erythrocyte velocity up
to 400%. High positive correlation existed between changes in CSF hydrogen
ion concentration and pial arteriolar diameter, suggesting metabolic
regulation of CBF through CSF/interstitial fluid hydrogen ion alterations
during the seizure.
ARTICLES
Brain microvascular hemodynamic responses to induced seizures
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