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Stroke, Vol 8, 218-221, Copyright © 1977 by American Heart Association

ARTICLES

Central nervous system angioendothelosis. A treatable multiple infarct dementia

JL Reinglass, J Muller, S Wissman and H Wellman

CNS neoplastic angioendothelosis is a treatable primary proliferative disorder of the endothelial cells of blood vessels characterized by a clinical neurological picture of multiple infarct dementia and an inordinate amount of local cerebral edema, so striking that it may simulate primary or metastatic central nervous system tumor. The malignant cells remain within the lumen of the vessels and rarely if ever metastasize or occur in peripheral blood. There is remarkable improvement in symptoms by treating with high dose steroids. Antimetabolites and irradiation are suggested means of additional treatment.

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