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Stroke. 1978;9:218-222

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Stroke, Vol 9, 218-222, Copyright © 1978 by American Heart Association

ARTICLES

Controlled trial of ornithine alpha ketoglutarate (OAKG) in patients with stroke

ML Woollard, RM Pearson, G Dorf, D Griffith and IM James

A double blind controlled trial of ornithine alpha-ketoglutarate (OAKG) was carried out on 50 patients admitted to the Royal Free and Royal Northern Hospitals, London, suffering from a recent stroke. Significant improvement was found in patients treated with OAKG when examined on the fifth day of therapy as compared to their control cases. The therapy was given for 5 days. When the patients in the treated and the control groups were compared 10 days after the beginning of treatment, there were no differences between the 2 groups. Implications of these findings are discussed.




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