on April 10, 2008
Published online before print April 10, 2008, doi: 10.1161/STROKEAHA.107.503482
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Submitted on October 24, 2007
From Department of Neurology, Universitätsklinikum Mannheim, University of Heidelberg, Mannheim, Germany. * To whom correspondence should be addressed. E-mail: kern{at}neuro.ma.uni-heidelberg.de.
Background and Purpose—To evaluate the potential of a new dynamic MRA sequence (DynAngio) based on arterial spin labeling for the assessment of intracranial collateral flow. Methods—Twelve patients with unilateral internal carotid artery obstruction were investigated. Different patterns of collateral flow were compared between DynAngio, transcranial color-coded duplex ultrasound, and time-of-flight MRA. Results—There was a good agreement between the methods, with sensitivities between 80% and 90%. Small collateral vessels were detected more frequently with DynAngio compared to time-of-flight MRA. Conclusion—DynAngio provides anatomic and similar to transcranial color-coded duplex ultrasound functional information on collateral flow for the assessment of intracranial hemodynamics.
Accepted on November 14, 2007
Assessment of Intracranial Collateral Flow by Using Dynamic Arterial Spin Labeling MRA and Transcranial Color-Coded Duplex Ultrasound
Fabrizio Sallustio MD;
Key words: carotid stenosis • collateral circulation • diagnostic imaging • magnetic resonance angiography • transcranial ultrasound