Published Online
on June 11, 2009

A more recent version of this article appeared on August 1, 2009

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Submitted on April 13, 2009
Revised on May 8, 2009
Accepted on May 12, 2009

Tissue Factor in Brain Is Not Saturated With Factor VIIa. Implications for Factor VIIa Dosing in Intracerebral Hemorrhage

Maureane Hoffman MD, PhD^* and Dougald M. Monroe PhD

From the Pathology & Laboratory Medicine Service, Durham VA Medical Center, Durham, NC; and the Division of Hematology/Oncology, University of North Carolina, Chapel Hill.

^* To whom correspondence should be addressed. E-mail: maureane.hoffman{at}med.va.gov.

Key words: hemorrhage • stroke • histology • blood coagulation • factor VIIa