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Published Online
on June 25, 2009

Stroke. 2009
Published online before print June 25, 2009, doi: 10.1161/STROKEAHA.109.556027
A more recent version of this article appeared on September 1, 2009
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Submitted on April 22, 2009
Accepted on May 26, 2009

Binge Drinking and Mortality From All Causes and Cerebrovascular Diseases in Korean Men and Women. A Kangwha Cohort Study

Jae Woong Sull PhD; Sang-Wook Yi MD, PhD; Chung Mo Nam PhD; and Heechoul Ohrr MD, PhD*

From the Institute for Health Promotion (J.W.S., H.O.), Graduate School of Public Health, Yonsei University, Seoul, Korea; the Department of Preventive Medicine and Public Health (S.-W.Y.), Kwandong University College of Medicine, Gangneung, Korea; and the Department of Preventive Medicine (C.M.N., H.O.), Yonsei University College of Medicine, Seoul, Korea.

* To whom correspondence should be addressed. E-mail: ohrr{at}yuhs.ac.

Background and Purpose—The purpose of this study was to examine the association between binge drinking and risks of mortality due to all causes of death with a focus on cerebrovascular disease in Korean men and women.

Methods—This study followed a cohort of 6291 residents in Kangwha County, aged ≥55 years in March 1985, for their cause-specific mortality for 20.8 years up to December 31, 2005. We calculated hazard ratio of mortality by experience or frequency of binge drinking using the Cox proportional hazard model. Binge drinking was defined as having ≥6 drinks on one occasion.

Results—In men, binge drinkers who drink daily had an increased risk of mortality from all causes (hazard ratio, 1.33; 95% CI, 1.11 to 1.60) as compared with nondrinkers. They showed much increased risks of mortality from total stroke (hazard ratio, 1.86; 95% CI, 1.16 to 2.99) and hemorrhagic stroke (hazard ratio, 3.39; 95% CI, 1.38 to 8.35). Female binge drinkers also showed an increased risk of mortality from cardiovascular disease as compared with female nondrinkers, but the outcome was not statistically significant.

Conclusions—The results of this study suggest that frequent binge drinking has a harmful effect on hemorrhagic stroke in Korean men. These findings need to be confirmed in further studies.


Key words: alcohol consumption • binge drinking • hemorrhagic stroke mortality