Stroke, Vol 24, 1473-1477, Copyright © 1993 by American Heart Association
H Rodgers, PD Aitken, JM French, RH Curless, D Bates and OF James
BACKGROUND AND PURPOSE: Previous studies have reported a U-shaped relation
between alcohol consumption and stroke. Those studies have been criticized
for failing to distinguish between lifelong abstainers from alcohol and
those who have given up drinking. METHODS: We examined current and previous
drinking habits of 364 cases of acute stroke and 364 community-based
control subjects matched for age, sex, and family practitioner. RESULTS:
Stroke patients were more likely to have been lifelong abstainers from
alcohol than were the control subjects. The odds ratio (OR) or lifelong
abstainers versus those who had ever drunk regularly was 2.36 (95%
confidence interval [CI], 1.67 to 3.37). No relation was found between
stroke and current nondrinkers. Current male heavy drinkers also had an
increased risk of stroke (OR, 2.88; 95% CI, 1.08 to 2.31). CONCLUSIONS:
Lifelong abstention from alcohol is associated with an increased risk of
stroke. Moderate alcohol consumption may protect against cerebrovascular
disease.
ARTICLES
Alcohol and stroke. A case-control study of drinking habits past and present
Department of Medicine (Geriatrics), University of Newcastle upon Tyne, UK.
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