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(Stroke. 2004;35:381.)
© 2004 American Heart Association, Inc.

Advances in Stroke 2003

Interventional Neuroradiology

D. Pelz, MD, FRCPC; P. Lylyk, MD M. Negoro, MD

From the Departments of Diagnostic Radiology and Nuclear Medicine and Clinical Neurological Sciences (D.M.P.), London Health Sciences Centre, London, Ontario, Canada; Clinica Medica Belgrano (P.L.), Buenos Aires, Argentina; and the Department of Neurosurgery (M.N.), Fujita Health University School of Medicine, Toyoake, Japan.

Correspondence to Dr David Pelz, Department of Diagnostic Radiology, London Health Sciences Centre, 339 Windermere Rd, London, Ontario, Canada N6A 5A5. E-mail pelz@uwo.ca

Key Words: Advances in Stroke • interventional neuroradiology

An extract of the first 250 words of the full text is provided, because this article has no abstract.

The year 2003 in interventional neuroradiology has been one of innovation, reflection, and anticipation. Innovation with the development of new devices for aneurysm therapy and carotid stenting, reflection on the results of the International Subarachnoid Aneurysm Study (ISAT) and the International Study of Unruptured Intracranial Aneurysms (ISUIA), and anticipation of the results of ongoing carotid stenting (CAS) versus endarterectomy (CEA) trials.

Cerebral Aneurysm Therapy

Healthy debate regarding optimal aneurysm treatment continues in the wake of ISAT.¹ Publication of the ISUIA² has revealed the benign nature of small (<7 mm) anterior circulation aneurysms and this will likely alter treatment strategies. Technological innovation continues with new coil designs incorporating bioactive materials such as fibroblast growth factor,^3,4 collagen,⁵ and polyglycolic acid/lactide.⁶ All of these materials have been shown to increase cellular response and healing potential in experimental aneurysms, and the widespread clinical use of Matrix coils⁶ (Boston Scientific) has shown promising results in humans, although there have been anecdotal reports of an increase in embolic complications. The challenge of treating wide-necked and complex aneurysms has been the focus of balloon remodeling⁷ and stent-assisted^8,9 techniques. The new Neuroform stent (Boston Scientific) is the first such device designed specifically for intracranial use and is rapidly gaining acceptance as an adjunct to the coiling of wide-necked aneurysms.^8,9 The introduction of more endovascular hardware can, however, increase the complexity and complication rates of these treatments.¹⁰ The dissemination of new imaging techniques such as rotational digital subtraction angiography will allow more accurate volumetric analysis of aneurysms to guide the use of . . . [Full Text of this Article]

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