Published online before print October 19, 2006, doi: 10.1161/01.STR.0000248207.87405.32
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(Stroke. 2006;37:2874.)
© 2006 American Heart Association, Inc.
Letters to the Editor |
Durability of Treatment of Intracranial Aneurysms With Hydrocoils Is Not Different From Standard Platinum Coils
Department of Radiology, St. Elisabeth Ziekenhuis, Tilburg, The Netherlands
To the Editor:
With interest we read the article by Gaba et al1 about the use of Hydrocoils for 50 intracranial aneurysms. The results were compared with a matched historical control group of 57 aneurysms treated with standard coils. We have some concerns about the methodology. First of all, aneurysm volume assessment assuming the aneurysm to be an ellipsoid is notoriously inaccurate2,3 and may account for the reported volumetric percentage occlusion of over 100% in more than half of the aneurysms. In addition, no standard angiographic follow-up interval to detect reopening was available and follow-up interval for aneurysms treated with standard coils was significantly longer. More aneurysms treated with standard coils were coiled with balloon remodelling (21 versus 7) indicating that more of these aneurysms had wide necks which may have influenced reopening rate.
A dazzling amount of confusing data are presented and interpreted toward better results of Hydrocoil. In fact, the bottom line of durability of treatment is the retreatment rate at follow-up, which is influenced by many other factors besides aneurysm volume and volumetric occlusion such as follow-up interval, proportion of partially thrombosed aneurysms and proportion of wide-necked aneurysms. A difference in retreatment of 4 of 41 aneurysms treated with Hydrocoil versus 7 of 41 aneurysms treated with standard coils is not significant, and both numbers are in the expected range of platinum coils.4,5 If these nonsignificant differences make the authors conclude that Hydrocoils are superior, a similar way of interpretation of results would conclude a higher complication rate (4% versus 0%) in aneurysms treated with Hydrocoils. One may wonder why such an effort is made to make the reader believe that results of Hydrocoils are better. Possibly the answer lies in the acknowledgments and colophon.
Acknowledgments
Disclosures
None.
References
- Gaba RC, Ansari SA, Roy SS, Marden FA, Viana MA, Malisch TW. Embolization of intracranial aneurysms with hydrogel-coated coils versus inert platinum coils: effects on packing density, coil length and quantity, procedure performance, cost, length of hospital stay, and durability of therapy. Stroke. 2006; 37: 1443–1450.
[Abstract/Free Full Text] - Piotin M, Daghman B, Mounayer C, Spelle L, Moret J. Ellipsoid approximation versus 3D rotational angiography in the volumetric assessment of intracranial aneurysms. AJNR Am J Neuroradiol. 2006; 27: 839–842.
[Abstract/Free Full Text] - Bescos JO, Slob MJ, Slump CH, Sluzewski M, van Rooij WJ. Volume measurement of intracranial aneurysms from 3D rotational angiography: improvement of accuracy by gradient edge detection. AJNR Am J Neuroradiol. 2005; 26: 2569–2572.
[Abstract/Free Full Text] - Sluzewski M, van Rooij WJ, Slob MJ, Bescos JO, Slump CH, Wijnalda D. Relation between aneurysm volume, packing, and compaction in 145 cerebral aneurysms treated with coils. Radiology. 2004; 231: 653–658.
[Abstract/Free Full Text] - Sluzewski M, van Rooij WJ, Rinkel GJ, Wijnalda D. Endovascular treatment of ruptured intracranial aneurysms with detachable coils: long-term clinical and serial angiographic results. Radiology. 2003; 227: 720–724.
[Abstract/Free Full Text]
Related Article:
- Response to Letter by van Rooij and Sluzewski
- Tim W. Malisch, Franklin A. Marden, and Ron C. Gaba
Stroke 2006 37: 2875.[Full Text] [PDF]
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