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(Stroke. 2007;38:e33.)
© 2007 American Heart Association, Inc.

Letters to the Editor

Response to Letter by Tsuda

Stefano Paolucci, MD; Maura Bragoni, MD, PhD; Paola Coiro, MD; Domenico De Angelis, MD; Francesca Romana Fusco, MD; Daniela Morelli, MD; Vincenzo Venturiero, MD Luca Pratesi, MD

Fondazione I.R.C.C.S. Santa Lucia, Rome, Italy

Response:

Dr Tsuda raises a very important issue. Indeed, hormonal differences could interfere with rehabilitation outcome and could explain, at least partly, the gender difference that we observed. In fact, it was reported that testosterone replacement during rehabilitation may improve functional outcome in males.¹ Moreover, in a study by Sipski and coworkers on the rehabilitation after spinal cord injury, men tended to do better functionally than women at time of discharge from rehabilitation.² A study of the effects of estrogen and testosterone levels on neurological recovery and the related effects of gender on functional potential is underway in our group.

Acknowledgments

Disclosures

None.

References

1. Morley JE, Haren MT, Kim MJ, Kevorkian R, Perry HM III. Testosterone, aging and quality of life. J Endocrinol Invest. 2005; 28: 76–80.[Medline] [Order article via Infotrieve]
2. Sipski ML, Jackson AB, Gomez-Marin O, Estores I, Stein A. Effects of gender on neurologic and functional recovery after spinal cord injury. Arch Phys Med Rehabil. 2004; 85: 1826–1836.[CrossRef][Medline] [Order article via Infotrieve]

This Article Extract Full Text (PDF) All Versions of this Article: 38/6/e33    most recent STROKEAHA.106.480301v1 Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Paolucci, S. Articles by Pratesi, L. Search for Related Content PubMed Articles by Paolucci, S. Articles by Pratesi, L.