Published Online
on April 15, 2004

A more recent version of this article appeared on May 1, 2004

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Submitted on December 2, 2003
Revised on December 24, 2003
Accepted on March 1, 2004

Catheter-Based Treatment for Patients With Acute Ischemic Stroke Ineligible for Intravenous Thrombolysis

Stephen R. Ramee MD^*; Rajesh Subramanian MBBS; Robert A. Felberg MD; Kevin L. McKinley MD; J. Stephen Jenkins MD; Tyrone J. Collins MD; Robert C. Dawson MD; and Christopher J. White MD

From Department of Cardiology (S.R.R., R.S., J.S.J., T.J.C., C.J.W.), Department of Neurology (R.A.F., K.L.M.), Division of Neuroradiology, Department of Neurosurgery (R.C.D.), Ochsner Clinic Foundation, New Orleans, La.

^* To whom correspondence should be addressed. E-mail: sramee{at}ochsner.org.

Background and Purpose--We present our single-center experience using catheter-based therapy for acute ischemic stroke patients who were not candidates for intravenous thrombolytic therapy.

Methods--Neurologic outcomes were assessed in patients with acute ischemic stroke, ineligible for intravenous thrombolysis, treated with an emergent catheter-based therapy.

Results--Nonparametric analysis of neurological outcomes demonstrated a benefit in National Institutes of Health Stroke Scale (NIHSS) at long-term follow-up (P=0.036). Independence in daily activities and improvement in NIHSS of 4 points were achieved in 38% and 56% of patients, respectively. Four patients (25%) died, including 2 patients (12.5%) who died from intracranial hemorrhage.

Conclusions--Catheter-based treatment offers a promising treatment strategy in patients with acute ischemic stroke ineligible for intravenous thrombolysis.

Key words: stroke, acute • stroke management • thrombolysis

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