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Published Online
on May 6, 2004

Stroke. 2004
Published online before print May 6, 2004, doi: 10.1161/01.STR.0000128705.63891.67
A more recent version of this article appeared on June 1, 2004
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Submitted on February 26, 2004
Accepted on March 2, 2004

Lower Serum Triglyceride Level Is Associated With Increased Stroke Severity

Tomasz Dziedzic MD*; Agnieszka Slowik MD; Elzbieta A. Gryz MD; and Andrzej Szczudlik MD, PhD

From the Department of Neurology, Jagiellonian University, Krakow, Poland.

* To whom correspondence should be addressed. E-mail: Dziedzic{at}neuro.cm-uj.krakow.pl.

Background and Purpose--A previous study showed that low triglyceride concentration predicts higher mortality after stroke. The aim of our study was to determine whether serum triglyceride level is associated with stroke severity on admission.

Methods--863 consecutive patients with acute ischemic stroke were included. Serum triglyceride level was measured within 36 hours after stroke onset. Stroke severity on admission was assessed using Scandinavian Stroke Scale (SSS). The patients were divided into 2 groups: those with severe stroke (SSS <=25) and those with mild/moderate stroke (SSS >25).

Results--Patients with severe stroke had significantly lower serum triglyceride level than patients with mild/moderate stroke (1.4±0.6 versus 1.7±1.3 mmol/L). After adjusting for age, sex, atrial fibrillation, diabetes mellitus, obesity, and ischemic heart disease, patients with triglyceride >2.3 mmol/L had lower risk of severe stroke than those with triglyceride <=2.3 mmol/L (OR: 0.58; 95% CI: 0.35 to 0.95).

Conclusions--Our results suggest that lower level of triglyceride is associated with the more severe stroke.


Key words: stroke • cholesterol