Published Online
on November 29, 2004

A more recent version of this article appeared on January 1, 2005

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Submitted on September 7, 2004
Revised on October 4, 2004
Accepted on October 4, 2004

Cognitive Function Before and After Surgery in Patients With Unruptured Intracranial Aneurysm

Yasunari Otawara MD^*; Kuniaki Ogasawara MD; Akira Ogawa MD; and Keiko Yamadate BSc

From the Department of Neurosurgery, Iwate Medical University (Y.O., K.O., A.O.), Morioka, Japan; and Department of Clinical Psychology, Tochinai Daini Hospital (K.Y.), Morioka, Japan.

^* To whom correspondence should be addressed. E-mail: ootawara-nsu{at}umin.ac.jp.

Background and Purpose--This prospective study investigated whether surgery for unruptured intracranial aneurysms (UIAs) affects cognitive function and cerebral blood flow (CBF).

Methods--Cognitive tests using the Wechsler Adult Intelligence Scale-Revised, Wechsler Memory Scale, Rey-Osterrieth Complex Figure test, and CBF measurements using single-photon emission computed tomography were performed before and after surgery for UIAs in 44 patients 70 years of age.

Results--Group-rate analysis showed the verbal intelligence quotient (IQ), performance IQ, full-scale IQ, and recall trial scores of the Rey-Osterrieth Complex Figure test all increased significantly after surgery, whereas the Wechsler Memory Scale and copy trial scores of the Rey-Osterrieth Complex Figure test were not significantly different. Event-rate analysis demonstrated that no patient showed impaired cognition. There was no significant difference between CBF before and after surgery.

Conclusions--Surgical repair for UIAs does not impair cognition or CBF in patients without postoperative restrictions in lifestyle.

Key words: cognition • intracranial aneurysm • surgery

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