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Published Online
on February 24, 2005

Stroke. 2005
Published online before print February 24, 2005, doi: 10.1161/01.STR.0000157591.61322.df
A more recent version of this article appeared on April 1, 2005
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Submitted on November 1, 2004
Revised on December 9, 2004
Accepted on December 15, 2004

A Simple 3-Item Stroke Scale. Comparison With the National Institutes of Health Stroke Scale and Prediction of Middle Cerebral Artery Occlusion

Oliver C. Singer MD*; Florian Dvorak MD; Richard du Mesnil de Rochemont MD; Heiner Lanfermann MD; Matthias Sitzer MD; and Tobias Neumann-Haefelin MD

From the Departments of Neurology (O.C.S., F.D., M.S., T.N.-H.) and Neuroradiology (R.d.M.d.R., H.L.), J.W. Goethe University, Frankfurt am Main, Germany.

* To whom correspondence should be addressed. E-mail: o.singer{at}em.uni-frankfurt.de.

Background and Purpose--The purpose of the study was to design a simple stroke scale that requires minimal training but reflects initial stroke severity and is predictive of middle cerebral artery (MCA) occlusion.

Methods--The new stroke scale assessed 3 parameters: (1) level of consciousness, (2) gaze, and (3) motor function. Each item was graded 0 to 2, where 0 indicated normal findings and 2 severe abnormalities (ie, profound drowsiness or worse, forced gaze deviation, and severe hemiparesis, respectively). During a study period of 11 months, patients presenting with acute stroke symptoms (onset ≤6 hours) were examined by a stroke neurologist assessing the new scale as well as the National Institutes of Health Stroke Scale (NIHSS). In addition, 83 patients received acute magnetic resonance angiography (MRA; as part of an acute stroke protocol).

Results--The new stroke scale was strongly associated with the NIHSS. Interobserver reliability of the new scale was high (intraclass correlation coefficient 0.947). Using post hoc analysis, a score of ≥4 predicted proximal vessel occlusion (T-segment or M1-segment occlusion of the MCA on MRA) almost as accurately (overall accuracy 0.86) as an NIHSS score of ≥14 (overall accuracy 0.93).

Conclusions--The new stroke scale reflects acute stroke severity well and predicts proximal MCA occlusion with reasonable accuracy. However, the clinical scale needs further evaluation before it can be recommended as a tool for the triage of acute stroke patients.


Key words: stroke assessment • stroke, acute • magnetic resonance imaging