Published Online
on February 24, 2005

A more recent version of this article appeared on April 1, 2005

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Submitted on August 26, 2004
Revised on December 7, 2004
Accepted on January 11, 2005

Cognitive Vitality and the Role of Stroke and Cardiovascular Disease Risk Factors

Philip B. Gorelick MD, MPH^*

From the Department of Neurology and Rehabilitation, University of Illinois College of Medicine at Chicago, Chicago, Ill.

^* To whom correspondence should be addressed. E-mail: pgorelic{at}uic.edu.

Background and Purpose--Vascular risk factors are common in the elderly, and some such as hypertension may be important predictors of cognitive impairment.

Summary of Review--In this article, the role that vascular risk factors may play in the prevention of vascular and nonvascular forms of cognitive impairment is reviewed.

Conclusions--Because vascular risk factors may have negative effects on brain structure and cognitive function, and because vascular risk factors may be present in midlife or possibly earlier, we may need to develop long-term intervention strategies to control or prevent vascular risk factors in an effort to preserve cognitive vitality as we age.

Key words: cognitive disorders • risk factors • vascular disorders

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