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on August 4, 2005

Stroke. 2005
Published online before print August 4, 2005, doi: 10.1161/01.STR.0000177475.30281.7f
A more recent version of this article appeared on September 1, 2005
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*Substance via MeSH
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*Secondhand Smoke
*Smoking
*Stroke
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Submitted on September 3, 2004
Revised on February 24, 2005
Accepted on March 3, 2005

Cigarette Smoking Among Spouses. Another Risk Factor for Stroke in Women

Adnan I. Qureshi MD*; M. Fareed; K. Suri MD; Jawad F. Kirmani MD; and Afshin A. Divani PhD

From the Zeenat Qureshi Stroke Research Center, Department of Neurology and Neurosciences, University of Medicine and Dentistry of New Jersey, Newark.

* To whom correspondence should be addressed. E-mail: aiqureshi{at}hotmail.com.

Background and Purpose--It is well known that passive exposure to cigarette smoking increases the risk of coronary events, but the effect on the risk of stroke is not well defined. We performed this study to determine the effect of cigarette smoking among spouses on the risk of developing stroke and ischemic stroke among a nationally representative sample of women.

Methods--We examined the association between history of smoking among spouses with the incidence of stroke in a national cohort of 5379 women who participated in the First National Health and Nutrition Examination Survey Epidemiologic Follow-Up Study.

Results--During a mean follow-up of 8.5 years, the risk was significantly increased for all strokes (relative risk, 5.7; 95% CI, 1.4 to 24) and ischemic stroke (relative risk, 4.8; 95% CI, 1.2 to 20) among cigarette-smoking women with a cigarette-smoking spouse compared with those with a nonsmoking spouse after adjusting for other cardiovascular risk factors.

Conclusion--The study provides new evidence linking spousal smoking to stroke.


Key words: smoking • stroke • women • minority groups • stroke, ischemic




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