Published Online
on September 8, 2005

A more recent version of this article appeared on October 1, 2005

This Article Full Text (PDF) All Versions of this Article: 36/10/2176    most recent 01.STR.0000181770.14869.cev1 Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Taschner, C. A. Articles by Pruvo, J.-P. Search for Related Content PubMed PubMed Citation Articles by Taschner, C. A. Articles by Pruvo, J.-P. Related Collections Acute Cerebral Hemorrhage Aneurysm, AVM, hematoma

Submitted on April 18, 2005
Revised on June 17, 2005
Accepted on July 4, 2005

Matrix Detachable Coils for the Endovascular Treatment of Intracranial Aneurysms. Analysis of Early Angiographic and Clinical Outcomes

Christian A. Taschner MD^*; Xavier Leclerc PhD; Henda Rachdi MD; Alexander Maia Barros MD; and Jean-Pierre Pruvo PhD

From the Department of Neuroradiology (C.A.T., X.L., H.R., A.M.B., J.-P.P.), Hôpital Roger Salengro, University Hospital Lille, France.

^* To whom correspondence should be addressed. E-mail: c.taschner{at}web.de.

Background and Purpose--Endovascular coil embolization has become an accepted alternative for the treatment of intracranial aneurysms. The purpose of this study was to evaluate the clinical safety and the angiographic stability of aneurysm occlusion with a new class of biologically active platinum coils after a 6-month period.

Methods--Twenty-five patients with 25 intracranial aneurysms were treated by selective embolization with a new coated bioactive coil (Matrix; Boston Scientific Neurovascular). Matrix coils were used alone in 6 patients and in combination with Guglielmi detachable coils (GDCs; Boston Scientific Neurovascular) in 19. Angiographic results, procedure-related complications, and adverse neurological events during the follow-up period were recorded. Magnetic resonance angiography was performed at 6 months in all patients.

Results--Initial angiographies demonstrated complete occlusion in 17 patients, residual neck in 7, and a persisting aneurysm in 1. The clinical follow-up showed stable results in all patients. The grade of aneurysm occlusion at 6 months improved in 4 patients, remained stable in 15, and deteriorated in 6. Three patients needed retreatment because of a major aneurysm recanalization. Angiographic recurrences in cases of aneurysms treated with a combination of Matrix coils and GDCs occurred within the expected range for bare platinum coils. Two of 3 patients needing retreatment had been treated with Matrix coils alone.

Conclusion--Stable results were obtained predominantly when Matrix coils were combined with bare platinum coils. A prospective, randomized study is necessary to assess the potential benefit of Matrix coils for patients treated by endovascular techniques.

Key words: aneurysm • cerebrovascular disorders

This article has been cited by other articles:

				C. Sherif, G. Bavinzski, C. Dorfer, F. Kanz, E. Schuster, and H. Plenk Jr Computerized Assessment of Angiographic Occlusion Rate and Coil Density in Embolized Human Cerebral Aneurysms AJNR Am. J. Neuroradiol., May 1, 2009; 30(5): 1046 - 1053. [Abstract] [Full Text] [PDF]

				P.M. White and J. Raymond Endovascular Coiling of Cerebral Aneurysms Using "Bioactive" or Coated-Coil Technologies: A Systematic Review of the Literature AJNR Am. J. Neuroradiol., February 1, 2009; 30(2): 219 - 226. [Abstract] [Full Text] [PDF]

				W.J. van Rooij, A.N. de Gast, and M. Sluzewski Results of 101 Aneurysms Treated with Polyglycolic/Polylactic Acid Microfilament Nexus Coils Compared with Historical Controls Treated with Standard Coils AJNR Am. J. Neuroradiol., May 1, 2008; 29(5): 991 - 996. [Abstract] [Full Text] [PDF]

				L. Pierot, X. Leclerc, A. Bonafe, S. Bracard, and for the French Matrix Registry Investigators Endovascular Treatment of Intracranial Aneurysms with Matrix Detachable Coils: Midterm Anatomic Follow-Up from a Prospective Multicenter Registry AJNR Am. J. Neuroradiol., January 1, 2008; 29(1): 57 - 61. [Abstract] [Full Text] [PDF]

				H.J. Cloft Matrix Reloaded AJNR Am. J. Neuroradiol., January 1, 2008; 29(1): 62 - 62. [Full Text] [PDF]

				D.J. Rivet, C.J. Moran, A. Mazumdar, T.K. Pilgram, C.P. Derdeyn, and D.T. Cross Single-Institution Experience with Matrix Coils in the Treatment of Intracranial Aneurysms: Comparison with Same-Center Outcomes with the Use of Platinum Coils AJNR Am. J. Neuroradiol., October 1, 2007; 28(9): 1736 - 1742. [Abstract] [Full Text] [PDF]

				D. Mitra, A. Herwadkar, C. Soh, and A. Gholkar Follow-Up of Intracranial Aneurysms Treated with Matrix Detachable Coils: A Single-Center Experience AJNR Am. J. Neuroradiol., February 1, 2007; 28(2): 362 - 367. [Abstract] [Full Text] [PDF]

				M. Bendszus and L. Solymosi Cerecyte Coils in the Treatment of Intracranial Aneurysms: A Preliminary Clinical Study AJNR Am. J. Neuroradiol., November 1, 2006; 27(10): 2053 - 2057. [Abstract] [Full Text] [PDF]

				V. Katsaridis, C. Papagiannaki, and C. Violaris Guglielmi Detachable Coils versus Matrix Coils: A Comparison of the Immediate Posttreatment Results of the Embolization of 364 Cerebral Aneurysms in 307 Patients: A Single-Center, Single-Surgeon Experience. AJNR Am. J. Neuroradiol., October 1, 2006; 27(9): 1841 - 1848. [Abstract] [Full Text] [PDF]

				C. A. Taschner, X. Leclerc, and J.-P. Pruvo Response to Letter by Wong et al Stroke, June 1, 2006; 37(6): 1364 - 1364. [Full Text] [PDF]

				G. K.C. Wong and W.S. Poon Thromboembolic Complications of Endovascular Aneurysm Occlusion Using Matrix Detachable Coils Stroke, June 1, 2006; 37(6): 1363 - 1363. [Full Text] [PDF]