Published Online
on November 23, 2005

A more recent version of this article appeared on January 1, 2006

This Article Full Text (PDF) All Versions of this Article: 37/1/63    most recent 01.STR.0000194955.34820.78v1 Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Jiang, B. Articles by Bao, Q.-j. Search for Related Content PubMed PubMed Citation Articles by Jiang, B. Articles by Bao, Q.-j. Related Collections Cerebrovascular disease/stroke Epidemiology

Submitted on May 2, 2005
Revised on September 27, 2005
Accepted on September 29, 2005

Incidence and Trends of Stroke and Its Subtypes in China. Results From Three Large Cities

Bin Jiang MD, MPH^*; Wen-zhi Wang MD; Honglei Chen MD, PhD; Zhen Hong MD; Qi-dong Yang MD; Sheng-ping Wu MD; Xiao-li Du MD; and Qiu-ju Bao MD

From the Department of Neuroepidemiology (B.J., W.-Z.W., S.-P.W., X.-L.D., Q.-J.B.), Beijing Neurosurgical Institute, China; Department of Neuroepidemiology (Z.H.), Institute of Neurology, Huashan Hospital, Medical College of Fudan University, Shanghai, China; Department of Neuroepidemiology (Q.-D.Y.), Institute of Neurology, Xiangya Hospital, Medical College of Zhongnan University, Changsha, People’s Republic of China; and Epidemiology Branch, National Institute of Environmental Health Sciences (H.C.), Research Triangle Park, NC.

^* To whom correspondence should be addressed. E-mail: bjyjiang{at}hotmail.com.

Background and Purpose--To examine the incidence and trends of stroke and its major subtypes during the 1990s in 3 cities in China.

Methods--Stroke cases registered between 1991 to 2000 were initially identified through the stroke surveillance networks established in Beijing, Shanghai, and Changsha, and then confirmed by neurologists.

Results--The age-standardized incidence rates per 100 000 person years of overall first-ever stroke were 135.0 (95% CI, 126.5 to 144.6) in Beijing, 76.1 (70.6 to 82.6) in Shanghai, and 150.0 (141.3 to 160.0) in Changsha during the 1990s. Incidence of ischemic stroke (IS) was highest in Beijing, followed by Changsha and Shanghai; for intracerebral hemorrhage (ICH), the highest rate was found in Changsha, followed by Beijing and Shanghai. The same order as ICH was also observed for subarachnoid hemorrhage. The age-adjusted incidence of overall stroke and ICH for individuals 55 years of age in our populations was generally higher than that from Western populations. During the 1990s, ICH incidence decreased significantly at a rate of 12.0% per year in Beijing, 4.4% in Shanghai, and 7.7% in Changsha; in contrast, except for Changsha, IS incidence increased in Beijing (5.0% per year) and Shanghai (7.7%).

Conclusions--There is a geographic variation in the incidence of stroke and its subtypes among these 3 cities, but the incidence of overall and hemorrhagic stroke in China is generally higher than that in the Western countries. Interestingly, the decrease in ICH and increase in IS during the past decade may reflect some underlying changes of risk factors in Chinese populations.

Key words: epidemiology • stroke • incidence

This article has been cited by other articles:

				L. Wu, Y. Shen, X. Liu, X. Ma, B. Xi, J. Mi, K. Lindpaintner, X. Tan, and X. Wang The 1425G/A SNP in PRKCH Is Associated With Ischemic Stroke and Cerebral Hemorrhage in a Chinese Population Stroke, September 1, 2009; 40(9): 2973 - 2976. [Abstract] [Full Text] [PDF]

				W. Liang, A. H. Lee, C. W. Binns, R. Huang, D. Hu, and Q. Zhou Tea Consumption and Ischemic Stroke Risk: A Case-Control Study in Southern China Stroke, July 1, 2009; 40(7): 2480 - 2485. [Abstract] [Full Text] [PDF]

				P. Appelros, B. Stegmayr, and A. Terent Sex Differences in Stroke Epidemiology: A Systematic Review Stroke, April 1, 2009; 40(4): 1082 - 1090. [Abstract] [Full Text] [PDF]

				S. K. Das and T. K. Banerjee Stroke: Indian Scenario Circulation, December 16, 2008; 118(25): 2719 - 2724. [Full Text] [PDF]

				B. Hallstrom, A.-C. Jonsson, C. Nerbrand, B. Norrving, and A. Lindgren Stroke Incidence and Survival in the Beginning of the 21st Century in Southern Sweden: Comparisons With the Late 20th Century and Projections Into the Future Stroke, January 1, 2008; 39(1): 10 - 15. [Abstract] [Full Text] [PDF]

				H C Hanger, T J Wilkinson, N Fayez-Iskander, and R Sainsbury The risk of recurrent stroke after intracerebral haemorrhage J. Neurol. Neurosurg. Psychiatry, August 1, 2007; 78(8): 836 - 840. [Abstract] [Full Text] [PDF]

				S. K. Das, T. K. Banerjee, A. Biswas, T. Roy, D. K. Raut, C. S. Mukherjee, A. Chaudhuri, A. Hazra, and J. Roy A Prospective Community-Based Study of Stroke in Kolkata, India Stroke, March 1, 2007; 38(3): 906 - 910. [Abstract] [Full Text] [PDF]

				A. Kitamura, Y. Nakagawa, M. Sato, H. Iso, S. Sato, H. Imano, M. Kiyama, T. Okada, H. Okada, M. Iida, et al. Proportions of Stroke Subtypes Among Men and Women >=40 Years of Age in an Urban Japanese City in 1992, 1997, and 2002 Stroke, June 1, 2006; 37(6): 1374 - 1378. [Abstract] [Full Text] [PDF]

				G. Xu, X. Liu, B. Jiang, and W.-z. Wang Has Stroke Shifted From Hemorrhagic to Ischemic in China? Stroke, April 1, 2006; 37(4): 941 - 942. [Full Text] [PDF]