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Published Online
on December 22, 2005

Stroke. 2005
Published online before print December 22, 2005, doi: 10.1161/01.STR.0000198809.76702.43
A more recent version of this article appeared on February 1, 2006
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Submitted on November 8, 2005
Revised on November 20, 2005
Accepted on November 22, 2005

Distribution of Carotid Arterial Lesions in Chinese Patients With Transient Monocular Blindness

Hung-Yi Hsu MD, PhD; Fu-Yi Yang MD; A-Ching Chao MD; Yen-Yu Chen MD; Chih-Ping Chung MD; Wen-Yung Sheng MS, MPH; and Han-Hwa Hu MD*

From the Section of Neurology (H-Y.H.), Taichung Veterans General Hospital, Taichung; Section of Neurovascular Diseases (F-Y.Y., Y-Y.C., C-P.C., W-Y.S., H-H.H.), Neurological Institute, Taipei Veterans General Hospital, Taipei; Neurological Department (A.-C.C.), Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung; and National Yang-Ming University (H.-Y.H., F-Y.Y., Y-Y.C., C-P.C., W-Y.S., H-H.H.), Taipei, Taiwan.

* To whom correspondence should be addressed. E-mail: hhhu{at}vghtpe.gov.tw.

Background and Purpose--Asian patients with cerebrovascular diseases have more intracranial atherosclerosis and less extracranial carotid artery stenosis compared with white patients. We systemically evaluated the distribution of carotid arterial lesions in Chinese patients with transient monocular blindness (TMB), which was rarely reported.

Methods--We prospectively evaluated 105 consecutive patients with TMB. All of the patients received ocular and physical examinations, blood tests for coagulation function and autoimmune diseases, and ultrasonography of cervical and intracranial arteries. All of the carotid lesions were confirmed by magnetic resonance angiography or cerebral angiography.

Results--Of the 36 (34.3%) patients with significant carotid stenosis (≥50%), 16 (15.2%) had extracranial carotid stenosis; 17 (16.2%) had carotid siphon stenosis; and 3 (2.9%) had both. The duration, onset, and patterns of visual loss were not different between patients with and without carotid arterial lesion.

Conclusions--This study signified the importance of carotid siphon stenosis as a probable underlying etiology for TMB in Chinese patients.


Key words: carotid arteries • Chinese • siphon stenosis • transient monocular blindness




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A-C. Chao, H.-Y. Hsu, C.-P. Chung, Y.-Y. Chen, M.-Y. Yen, W.-J. Wong, and H.-H. Hu
Altered Retrobulbar Hemodynamics in Patients Who Have Transient Monocular Blindness Without Carotid Stenosis
Stroke, April 1, 2007; 38(4): 1377 - 1379.
[Abstract] [Full Text] [PDF]