Published Online
on March 2, 2006

A more recent version of this article appeared on April 1, 2006

This Article Full Text (PDF) All Versions of this Article: 37/4/1028    most recent 01.STR.0000206459.73897.a3v1 Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Niimi, Y. Articles by Berenstein, A. Search for Related Content PubMed PubMed Citation Articles by Niimi, Y. Articles by Berenstein, A. Related Collections Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage Angiography Aneurysm, AVM, hematoma

Submitted on September 28, 2005
Revised on November 23, 2005
Accepted on November 28, 2005

Endosaccular Treatment of Intracranial Aneurysms Using Matrix Coils. Early Experience and Midterm Follow-Up

Yasunari Niimi MD, PhD^*; Joon Song MD; Mary Madrid RN, PhD; and Alejandro Berenstein MD

From the Center for Endovascular Surgery, Hyman-Newman Institute of Neurology and Neurosurgery, Roosevelt Hospital, New York, NY.

^* To whom correspondence should be addressed. E-mail: yniimi{at}chpnet.org.

Background and Purpose--The authors report their experience using Matrix coils in the treatment of cerebral aneurysms.

Methods--The outcomes of 72 consecutive patients (76 aneurysms) who underwent coiling using Matrix coils at our institution were retrospectively analyzed.

Results--Seventy-four aneurysms in 70 patients were coiled using Matrix coils (ranging 3% to 100% by coil length; mean 68.8%). Two patients underwent regular platinum coil embolization after failed Matrix coil placement. Thirty-two (42%) ruptured aneurysms were acutely treated. In 46 aneurysms, Matrix composed >50% of coil length. Complete aneurysm occlusion was obtained in 13 aneurysms (17.6%), neck remnant in 30 (40.5%), and dome filling in 31 (41.9%). Procedural morbidity and mortality rates were 1.4% and 1.4%, respectively. Angiographic follow-up was obtained in 63.5% (47 of 74 aneurysms; average 12.2 months; range 0 to 34). In these 47 angiographically followed aneurysms, the overall recanalization rate was 57.4%. In aneurysms with >50% Matrix coils, 76.1% had angiographic follow-up (35 of 46), and in this group, the overall recanalization rate was 54.3% (19 of 35): 25% (1 of 4) for very small (<5 mm); 33% (4 of 12) for small-size (<10 mm)/small-neck (<4 mm); and 63% (5 of 8) for small-size/wide-neck (4 mm). A total of 82% (9 of 11) recanalization occurred in large aneurysms (10 to 25 mm). Ten aneurysms (21.3%; 10 of 47) underwent retreatment. Clinical follow-up was obtained in 61 (86%) patients (average 15 months; range 1 to 37): 87% of patients were Glasgow Outcome Scale 4 or 5.

Conclusion--The use of Matrix coils resulted in worse recanalization rates than that reported for Guglielmi detachable bare platinum coils.

Key words: cerebral aneurysm • embolization • therapeutic

This article has been cited by other articles:

				I. Linfante, M.J. DeLeo III, M.J. Gounis, C.S. Brooks, and A.K. Wakhloo Cerecyte versus Platinum Coils in the Treatment of Intracranial Aneurysms: Packing Attenuation and Clinical and Angiographic Midterm Results AJNR Am. J. Neuroradiol., September 1, 2009; 30(8): 1496 - 1501. [Abstract] [Full Text] [PDF]

				D.F. Kallmes, Y.H. Ding, D. Dai, R. Kadirvel, D.A. Lewis, and H.J. Cloft A Second-Generation, Endoluminal, Flow-Disrupting Device for Treatment of Saccular Aneurysms AJNR Am. J. Neuroradiol., June 1, 2009; 30(6): 1153 - 1158. [Abstract] [Full Text] [PDF]

				P.M. White and J. Raymond Endovascular Coiling of Cerebral Aneurysms Using "Bioactive" or Coated-Coil Technologies: A Systematic Review of the Literature AJNR Am. J. Neuroradiol., February 1, 2009; 30(2): 219 - 226. [Abstract] [Full Text] [PDF]

				M. Piotin, L. Spelle, C. Mounayer, C. Loureiros, A. Ghorbani, and J. Moret Intracranial Aneurysms Coiling With Matrix: Immediate Results in 152 Patients and Midterm Anatomic Follow-Up From 115 Patients Stroke, January 1, 2009; 40(1): 321 - 323. [Abstract] [Full Text] [PDF]

				S. Holmin, T. Krings, A. Ozanne, J.-P. Alt, A. Claes, W. Zhao, H. Alvarez, G. Rodesch, and P. Lasjaunias Intradural Saccular Aneurysms Treated by Guglielmi Detachable Bare Coils at a Single Institution Between 1993 and 2005: Clinical Long-Term Follow-Up for a Total of 1810 Patient-Years in Relation to Morphological Treatment Results Stroke, August 1, 2008; 39(8): 2288 - 2297. [Abstract] [Full Text] [PDF]

				W.J. van Rooij, A.N. de Gast, and M. Sluzewski Results of 101 Aneurysms Treated with Polyglycolic/Polylactic Acid Microfilament Nexus Coils Compared with Historical Controls Treated with Standard Coils AJNR Am. J. Neuroradiol., May 1, 2008; 29(5): 991 - 996. [Abstract] [Full Text] [PDF]

				D. Butteriss, A. Gholkar, D. Mitra, D. Birchall, and V. Jayakrishnan Single-Center Experience of Cerecyte Coils in the Treatment of Intracranial Aneurysms: Initial Experience and Early Follow-Up Results AJNR Am. J. Neuroradiol., January 1, 2008; 29(1): 53 - 56. [Abstract] [Full Text] [PDF]

				L. Pierot, X. Leclerc, A. Bonafe, S. Bracard, and for the French Matrix Registry Investigators Endovascular Treatment of Intracranial Aneurysms with Matrix Detachable Coils: Midterm Anatomic Follow-Up from a Prospective Multicenter Registry AJNR Am. J. Neuroradiol., January 1, 2008; 29(1): 57 - 61. [Abstract] [Full Text] [PDF]

				H.J. Cloft Matrix Reloaded AJNR Am. J. Neuroradiol., January 1, 2008; 29(1): 62 - 62. [Full Text] [PDF]

				D.J. Rivet, C.J. Moran, A. Mazumdar, T.K. Pilgram, C.P. Derdeyn, and D.T. Cross Single-Institution Experience with Matrix Coils in the Treatment of Intracranial Aneurysms: Comparison with Same-Center Outcomes with the Use of Platinum Coils AJNR Am. J. Neuroradiol., October 1, 2007; 28(9): 1736 - 1742. [Abstract] [Full Text] [PDF]

				R. Kadirvel, Y.-H. Ding, D. Dai, D. A. Lewis, H. J. Cloft, and D. F. Kallmes Molecular Indices of Apoptosis Activation in Elastase-Induced Aneurysms After Embolization With Platinum Coils Stroke, October 1, 2007; 38(10): 2787 - 2794. [Abstract] [Full Text] [PDF]

				M. Bendszus, A. J. Bartsch, and L. Solymosi Endovascular Occlusion of Aneurysms Using a New Bioactive Coil: A Matched Pair Analysis With Bare Platinum Coils Stroke, October 1, 2007; 38(10): 2855 - 2857. [Abstract] [Full Text] [PDF]

				A.K. Wakhloo, M.J. Gounis, J.S. Sandhu, N. Akkawi, A.E. Schenck, and I. Linfante Complex-Shaped Platinum Coils for Brain Aneurysms: Higher Packing Density, Improved Biomechanical Stability, and Midterm Angiographic Outcome AJNR Am. J. Neuroradiol., August 1, 2007; 28(7): 1395 - 1400. [Abstract] [Full Text] [PDF]

				I. Linfante and A. K. Wakhloo Brain Aneurysms and Arteriovenous Malformations: Advancements and Emerging Treatments in Endovascular Embolization Stroke, April 1, 2007; 38(4): 1411 - 1417. [Abstract] [Full Text] [PDF]

				J. Raymond, I. Salazkin, G. Gevry, and T.N. Nguyen Interventional Neuroradiology: The Role of Experimental Models in Scientific Progress AJNR Am. J. Neuroradiol., March 1, 2007; 28(3): 401 - 405. [Abstract] [Full Text] [PDF]

				D. Mitra, A. Herwadkar, C. Soh, and A. Gholkar Follow-Up of Intracranial Aneurysms Treated with Matrix Detachable Coils: A Single-Center Experience AJNR Am. J. Neuroradiol., February 1, 2007; 28(2): 362 - 367. [Abstract] [Full Text] [PDF]

				D. M. Pelz, E. I. Levy, and L. N. Hopkins Advances in Interventional Neuroradiology 2006 Stroke, February 1, 2007; 38(2): 232 - 234. [Full Text] [PDF]