Published Online
on December 28, 2006

A more recent version of this article appeared on February 1, 2007

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Submitted on June 22, 2006
Accepted on September 18, 2006

Insular Cortex Hypoperfusion and Acute Phase Blood Glucose After Stroke. A CT Perfusion Study

Fiona C. Moreton BSc; Michael McCormick MRCP; and Keith W Muir MD, FRCP^*

From Division of Clinical Neurosciences, University of Glasgow, Institute of Neurological Sciences, Southern General Hospital, Glasgow, Scotland, UK.

^* To whom correspondence should be addressed. E-mail: k.muir{at}clinmed.gla.ac.uk.

Background and Purpose--Insular cortex ischemia is proposed to mediate a sympathetic stimulus that leads to acute hyperglycemia after stroke.

Methods--We retrospectively analyzed insular perfusion on perfusion CT (median 180 minutes after onset) in 35 patients.

Results--We found no association of hypoperfusion (relative cerebral blood flow <0.51) with early (<6 hours) or delayed (<72 hours) hyperglycemia, or hemispheric lateralization.

Conclusions--Insular cortex hypoperfusion <6 hours after stroke onset was not associated with hyperglycemia.

Key words: blood glucose • cerebral blood flow • hyperglycemia • insula • perfusion CT

This article has been cited by other articles:

				M. T. McCormick, K. W. Muir, C. S. Gray, and M. R. Walters Management of Hyperglycemia in Acute Stroke: How, When, and for Whom? Stroke, July 1, 2008; 39(7): 2177 - 2185. [Full Text] [PDF]