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(Stroke. 1970;1:178.)
© 1970 American Heart Association, Inc.


Transient Cerebral Ischemic Attacks Associated With Subacute Bacterial Endocarditis

ROBERT G. SIEKERT M.D.1 ROYDEN H. JONES JR. M.D.2

1 Mayo Clinic and Mayo Foundation: Section of Neurology
2 Mayo Graduate School of Medicine (University of Minnesota), Rochester; Resident in Neurology

The case histories are given of 12 patients who had transient cerebral attacks in association with subacute bacterial endocarditis. The attacks are similar to those that accompany atherosclerotic occlusive cerebrovascular disease. All patients had manifestations of general illness, particularly fever, malaise, and elevated sedimentation rate. Subsequently, cerebral infarcts occurred in three patients and cerebral hemorrhages in four patients. A definite relationship between anticoagulant therapy and hemorrhage could not be established.


Key Words: cerebral infarction • cerebral hemorrhage • anticoagulant therapy • cerebral embolism • sedimentation rate