This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Stehbens, W. E. Search for Related Content PubMed PubMed Citation Articles by Stehbens, W. E.

Stroke, Vol 12, 643-647, Copyright © 1981 by American Heart Association

ARTICLES

Chronic vascular changes in the walls of experimental berry aneurysms of the aortic bifurcation in rabbits

WE Stehbens

Experimental berry aneurysms were fashioned from an autogenous venous transplant by microvascular surgery at the aortic bifurcation of rabbits maintained on a stock diet. Structural changes in the aneurysms and in the host aorta were studied for periods up to 3 years 9 months postoperatively. Phlebosclerosis developed in the aneurysms and progressed to severe fibrosis, calcification, ossification, mural thrombosis and lipid deposition resembling human atherosclerosis, with eventual loss of the media. The host aorta exhibited pronounced intimal thickening at the bifurcation. The experiments demonstrated the importance of hemodynamic stress in the accelerated production of the degenerative changes in the walls of berry aneurysms.

This article has been cited by other articles:

				M. Abedin, Y. Tintut, and L. L. Demer Mesenchymal Stem Cells and the Artery Wall Circ. Res., October 1, 2004; 95(7): 671 - 676. [Abstract] [Full Text] [PDF]

				N. H. Fujiwara and D. F. Kallmes Healing Response in Elastase-Induced Rabbit Aneurysms after Embolization with a New Platinum Coil System AJNR Am. J. Neuroradiol., August 1, 2002; 23(7): 1137 - 1144. [Abstract] [Full Text] [PDF]

				W. Stehbens In Re: Histologic and Morphologic Comparison of Experimental Aneurysms with Human Intracranial Aneurysms AJNR Am. J. Neuroradiol., October 1, 2000; 21(9): 1770 - 1770. [Full Text]

				T. Abruzzo, H. J. Cloft, and G. G. Shengelaia Reply AJNR Am. J. Neuroradiol., October 1, 2000; 21(9): 1771 - 1773. [Full Text]