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Stroke, Vol 14, 682-687, Copyright © 1983 by American Heart Association
AC Breuer, AJ Furlan, MR Hanson, RJ Lederman, FD Loop, DM Cosgrove, RL Greenstreet and FG Estafanous
A prospective analysis of 421 patients undergoing coronary artery bypass
graft (CABG) surgery as the sole cardiac procedure was carried out to
assess the frequency of central nervous system (CNS) complications. In all,
451 variables were assessed in each patient. Stroke occurred in 5.2% but
was severe in only 2%. Prolonged encephalopathy occurred in 11.6% but
usually resolved before discharge. No statistically significant pre- or
intraoperative risk variables for CNS complications were found;
specifically, age or pump times in excess of two hours were not significant
factors. Postoperative use of an intraaortic balloon pump and pressor
agents were significantly correlated with prolonged encephalopathy. The
frequency of CNS injury in CABG surgery is similar to that in other forms
of open heart surgery, and there has been little change in the frequency of
CNS complications over the past seven years. Possible mechanisms of CNS
damage during CABG surgery are discussed.
ARTICLES
Central nervous system complications of coronary artery bypass graft surgery: prospective analysis of 421 patients
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