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Stroke, Vol 20, 295-298, Copyright © 1989 by American Heart Association

ARTICLES

An alternative view of heparin anticoagulation in acute focal brain ischemia

SJ Phillips
Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

Despite the lack of evidence of its efficacy, heparin therapy has been recommended for selected patients with ischemic stroke syndromes. However, heparin has procoagulant effects on platelet function and a propensity to produce serious side effects. When these factors are considered, heparin loses its appeal as a therapeutic agent for patients with acute focal cerebral ischemia.

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