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Stroke, Vol 20, 473-476, Copyright © 1989 by American Heart Association


ARTICLES

Morning increase in onset of ischemic stroke

JR Marler, TR Price, GL Clark, JE Muller, T Robertson, JP Mohr, DB Hier, PA Wolf, LR Caplan and MA Foulkes
Division of Stroke and Trauma, National Institute of Neurological and Communicative Disorders and Stroke, Bethesda, MD 20892.

The time of onset of ischemic stroke was determined for 1,167 of 1,273 patients during the collection of data by four academic hospital centers between June 30, 1983, and June 30, 1986. More strokes occurred in awake patients from 10:00 AM to noon than during any other 2-hour interval. The incidence of stroke onset declined steadily during the remainder of the day and early evening. The onset of stroke is least likely to occur in the late evening, before midnight.


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