Stroke, Vol 20, 718-724, Copyright © 1989 by American Heart Association
TJ Ingall, JP Whisnant, DO Wiebers and WM O'Fallon
We studied subarachnoid hemorrhage in the population of Rochester,
Minnesota, for the 40-year period from 1945 through 1984. The average
annual incidence rate of subarachnoid hemorrhage in Rochester has remained
constant at approximately 11 per 100,000 population. Age- specific
incidence rates increased with age. However, the average annual mortality
rate for subarachnoid hemorrhage in Rochester has shown a decreasing trend,
from 6.8 per 100,000 population in 1955-1964 to 4.3 in 1975-1984. It is
likely that this is due to a decrease in case-fatality rates from 57% in
1945-1974 to 42% in 1975-1984 (p = 0.10). This decreasing trend was also
evident in annual mortality rates from subarachnoid hemorrhage for US white
men and women. The reason for the improved case-fatality rate is unclear,
but it may be related to changes in management. The interval from onset of
subarachnoid hemorrhage to surgery decreased from a median of 12 days in
1975-1979 to 2 days in 1980-1984, and of those who survived to receive
medical attention, more patients received some form of medical treatment in
1980-1984. Whether either or both of these changes have led to the decrease
in the case-fatality rate is uncertain.
ARTICLES
Has there been a decline in subarachnoid hemorrhage mortality?
Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905.
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