Stroke, Vol 22, 1021-1025, Copyright © 1991 by American Heart Association
H Palomaki
To determine if a history of snoring is a risk factor for brain infarction,
I conducted a case-control study of risk factors for ischemic stroke using
177 consecutive male patients aged 16-60 (mean 49) years with acute brain
infarction. For each patient I chose an age- matched (+/- 6 years) male
control. Arterial hypertension, coronary heart disease, snoring (habitually
or often), and heavy drinking (greater than 300 g/wk) were risk factors in
the stepwise multiple logistic regression analysis. The odds ratio of
snoring for brain infarction was 2.13. By McNemar's test this association
increased strongly if a history of sleep apnea, excessive daytime
sleepiness, and obesity were all present with snoring (odds ratio 8.00). My
study indicates that snoring may be a risk factor for ischemic stroke,
possibly because of the higher prevalence of an obstructive sleep apnea
syndrome among snorers than nonsnorers.
ARTICLES
Snoring and the risk of ischemic brain infarction
Helsinki University Central Hospital, Finland.
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