Stroke, Vol 23, 798-803, Copyright © 1992 by American Heart Association
K Ueda, H Kawano, Y Hasuo and M Fujishima
BACKGROUND AND PURPOSE: We sought to determine the type-specific prevalence
of dementia and its risk factors in elderly persons from the Japanese
community of Hisayama. METHODS: We studied the prevalence of dementia in
887 Hisayama residents (353 men and 534 women) aged 65 years or older
(screening rate, 94.6%) using various items of clinical information,
neurological examination, and dementia scales. We also studied brain
morphology in 50 of 59 determined to have dementia by computed tomography
or autopsy during the subsequent 54-month period. Factors relevant to
dementia were compared between 27 patients with vascular dementia and 789
control subjects without dementia in a retrospective fashion. RESULTS: The
prevalence rate of dementia among Hisayama residents aged 65 or older was
estimated at 6.7%, with a females to males ratio of 1:2. Among 50 cases of
dementia in which brain morphology was examined, the frequency of vascular
dementia was 56%; this rate was 2.2 times higher than that for senile
dementia of the Alzheimer type. Aging, hypertension, electrocardiographic
abnormalities, and high hematocrit were significantly (p less than 0.05)
and independently associated with the occurrence of vascular dementia.
CONCLUSIONS: Prevalence of dementia among the Hisayama residents was
relatively identical to that previously reported, but vascular dementia was
more predominant. Risk factors for vascular dementia were similar to those
for lacunar infarcts. Control of hypertension may be a key to reducing
dementia among the Japanese population.
ARTICLES
Prevalence and etiology of dementia in a Japanese community
Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
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