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(Stroke. 1997;28:453-455.)
© 1997 American Heart Association, Inc.

Articles

Infection-Associated Cervical Artery Dissection

Three Cases

Armin J. Grau, MD; Tobias Brandt, MD; Michael Forsting, MD; Ralph Winter, MD Werner Hacke, MD

the Neurology Department, University of Heidelberg (Germany).

Correspondence to Armin J. Grau, MD, Neurology Department, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.

Background The pathogenesis of cervical artery dissection remains unknown. Infection-mediated damage of the arterial wall may be one contributing mechanism. We present three male patients with respiratory infection prior to cervical artery dissection.

Case Descriptions Case 1: During an upper respiratory tract infection, a 49-year-old patient developed bilateral carotid and vertebral artery dissection with complete vessel restitution. Case 2: Within 3 years, a 40-year-old patient experienced two episodes of bilateral internal carotid artery dissection, both preceded by febrile upper respiratory tract infection. Case 3: A 52-year-old patient developed right-sided and, 2 years later, left-sided internal carotid artery dissection, each following upper respiratory tract infection.

Conclusions Infection may be a trigger factor in the pathogenesis of cervical artery dissection.

Key Words: carotid arteries • dissection • infection

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