This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Feigin, V. L. Articles by Whisnant, J. P. Search for Related Content PubMed PubMed Citation Articles by Feigin, V. L. Articles by Whisnant, J. P.

(Stroke. 1998;29:34-39.)
© 1998 American Heart Association, Inc.

Original Contributions

Risk Factors for Ischemic Stroke in a Russian Community

A Population-Based Case-Control Study

Valery L. Feigin, MD, DSc; David O. Wiebers, MD; Yury P. Nikitin, MD, DSc; W. Michael O'Fallon, PhD; Jack P. Whisnant, MD

From the Department of Health Sciences Research (V.L.F., D.O.W., W.M.O., J.P.W.) and the Division of Cerebrovascular Diseases (D.O.W., W.M.O., J.P.W.), Mayo Clinic and Mayo Foundation, Rochester, Minn; and the Cerebrovascular Disease Center, Institute of Internal Medicine Siberian Branch of the Russian Academy of Medical Science, Novosibirsk, Russia (V.L.F., Y.P.N.).

Background and Purpose—This study was conducted to determine the risk factors for ischemic stroke in a defined Russian population.

Methods—Our data are based on a population-based case-control study of 237 patients with first-ever ischemic stroke and 237 age- and sex-matched controls. Logistic regression methods for matched pairs were used to estimate the relative risk for the variables studied.

Results—In a multivariate analysis, hypertension, left ventricular hypertrophy on electrocardiography, ischemic heart disease, mitral valve disease, current cigarette smoking, and high body mass index were significant and independent risk factors for ischemic stroke in this Russian community.

Conclusions—The significant risk factors for ischemic stroke in Novosibirsk are similar to those from other populations and cohorts. This study, the first of stroke risk factors in Russia, has implications for clinical practice and the planning of stroke prevention in the population.

Key Words: epidemiology • ischemic • risk factors • stroke

This article has been cited by other articles:

				E. Flossmann, U. G.R. Schulz, and P. M. Rothwell Systematic Review of Methods and Results of Studies of the Genetic Epidemiology of Ischemic Stroke Stroke, January 1, 2004; 35(1): 212 - 227. [Abstract] [Full Text] [PDF]

				M L Bots, Y Nikitin, J T Salonen, P C Elwood, S Malyutina, A Freire de Concalves, J Sivenius, A Di Carlo, P Lagiou, J Tuomilehto, et al. Left ventricular hypertrophy and risk of fatal and non-fatal stroke. EUROSTROKE: a collaborative study among research centres in Europe J Epidemiol Community Health, February 1, 2002; 56(90001): i8 - 13. [Abstract] [Full Text] [PDF]

				A Arboix, I Padilla, J Massons, L Garcia-Eroles, E Comes, and C Targa Clinical study of 222 patients with pure motor stroke J. Neurol. Neurosurg. Psychiatry, August 1, 2001; 71(2): 239 - 242. [Abstract] [Full Text] [PDF]