(Stroke. 1999;30:2617.)
© 1999 American Heart Association, Inc.
Original Contributions |
Outcome After Endovascular Treatment of Hunt and Hess Grade IV or V Aneurysms
Comparison of Anterior Versus Posterior Circulation
From the Departments of Neurology (C.K., H.C.H.) and Neuroradiology (C.G., U.G., H.Z.), University Hospital Eppendorf, Hamburg, Germany.
Correspondence to Christoph Groden, MD, Department of Neuroradiology, University Hospital Eppendorf, Martinstr 52, D-20246 Hamburg, Germany. E-mail groden{at}uke.uni-hamburg.de
Background and Purpose—The most common cause of poor treatment outcome in patients suffering aneurysmal subarachnoid hemorrhage is cerebral vasospasm, especially in cases of poor Hunt and Hess grades (IV and V). A further prognostic factor in surgically treated patients is aneurysm localization. The aim of the present retrospective study is to compare the endovascular treatment outcome in such poor-grade patients according to aneurysm localization in either the anterior (AC) or posterior (PC) circulation.
Methods—Forty poor-grade patients admitted between 1993 and July 1998 were treated by endovascular approach within 23 days after aneurysm rupture. Eighteen had aneurysms in the AC, 22 in the PC. Mean treatment delay was 4 days after rupture and median, 2 days. One patient showed multiple aneurysms. In 36 cases, aneurysms were occluded by Guglielmi detachable coils; in 4 cases, by parent vessel balloon occlusion.
Results—The incidence of delayed ischemic neurological dysfunction or cerebral infarct due to vasospasm did not differ significantly between the AC and PC groups. Two procedure-related complications with clinical effect were observed in each group. At 6 months’ follow-up, the result was good in 5 patients and poor in 13 in the AC group and good in 11 patients and poor in 11 in the PC group.
Conclusions—Given comparable incidence of vasospasm in poor-grade
patients, a tendency toward better treatment outcome was found in
patients with aneurysms in the posterior circulation
(
2=2.04; P=0.15) than in the anterior
circulation. Endovascular therapy for poor-grade patients is
recommended, as are further studies to determine treatment differences.
Key Words: aneurysm • subarachnoid hemorrhage • endovascular therapy • vasospasm • outcome
This article has been cited by other articles:
 |
|
 |
|
  J. B. Bederson, E. S. Connolly Jr, H. H. Batjer, R. G. Dacey, J. E. Dion, M. N. Diringer, J. E. Duldner Jr, R. E. Harbaugh, A. B. Patel, and R. H. Rosenwasser Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage: A Statement for Healthcare Professionals From a Special Writing Group of the Stroke Council, American Heart Association Stroke, March 1, 2009; 40(3): 994 - 1025. [Full Text] [PDF]
|
|
|
|
 |
|
 B. Lubicz, X. Leclerc, J.-Y. Gauvrit, J.-P. Lejeune, and J.-P. Pruvo Endovascular Treatment of Ruptured Intracranial Aneurysms in Elderly People AJNR Am. J. Neuroradiol., April 1, 2004; 25(4): 592 - 595. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Vogel, R. Verreault, J.-F. Turcotte, M. Kiesmann, and M. Berthel Review Article. Intracerebral Aneurysms: A Review With Special Attention to Geriatric Aspects J. Gerontol. A Biol. Sci. Med. Sci., June 1, 2003; 58(6): M520 - 524. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. U. Weir, M. L. Marcellus, H. M. Do, G. K. Steinberg, and M. P. Marks Aneurysmal Subarachnoid Hemorrhage in Patients with Hunt and Hess Grade 4 or 5: Treatment Using the Guglielmi Detachable Coil System AJNR Am. J. Neuroradiol., April 1, 2003; 24(4): 585 - 590. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. C. Johnston, R. T. Higashida, D. L. Barrow, L. R. Caplan, J. E. Dion, G. Hademenos, L. N. Hopkins, A. Molyneux, R. H. Rosenwasser, F. Vinuela, et al. Recommendations for the Endovascular Treatment of Intracranial Aneurysms: A Statement for Healthcare Professionals from the Committee on Cerebrovascular Imaging of the American Heart Association Council on Cardiovascular Radiology Stroke, October 1, 2002; 33(10): 2536 - 2544. [Full Text] [PDF]
|
|
|
|
|
|
S. Bracard, A. Lebedinsky, R. Anxionnat, J. M. Neto, G. Audibert, Y. Long, and L. Picard Endovascular Treatment of Hunt and Hess Grade IV and V Aneuryms AJNR Am. J. Neuroradiol., June 1, 2002; 23(6): 953 - 957. [Abstract] [Full Text] [PDF]
|
|