(Stroke. 2000;31:791.)
© 2000 American Heart Association, Inc.
Letters to the Editor |
STICH, Department of Neurosurgery, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
To the Editor:
We were pleased to see the report of the randomized feasibility study of early surgical treatment for supratentorial intracerebral hemorrhage by Zuccarello et al.1
This study provides yet more evidence of the need for a large randomized trial of surgery for spontaneous intracerebral hemorrhage, as has been shown previously.2 3 4 5 6 7 8 We wish to inform your readers of the progress of such a trial. The STICH (Surgical Trial in Intracerebral Haemorrhage) has been funded by the Medical Research Council (UK) but is open to centers from any country, and we would invite interested centers to contact us.
STICH is a multicenter, pragmatic, randomized trial aiming to recruit 1000 patients. The trial is managed by a team at Newcastle University (UK). To date, we have 68 centers from the United Kingdom, Germany, Sweden, Spain, Hungary, Poland, Czech Republic, Italy, Belgium, Greece, Ukraine, Russia, South Africa, Hong Kong and the United States. Randomization is performed by telephoning the Randomisation Service at Oxford University (UK) after identifying a patient, gaining consent, and completing a randomization form. An additional form is completed 2 weeks later (or at death or discharge if earlier) to record patient status at this point and details of any surgery or adverse events. Follow-up at 6 months is obtained by the team in Newcastle, who send a questionnaire to each patient for completion.
So far we have recruited 273 patients to the study, and complete
6-month follow-up data has been achieved for 130 patients. The trial is
being carried
Department of Neurology, University of Cincinnati, Cincinnati, Ohio
Department of Neurology, Mayo Clinic, Jacksonville, Florida
Service de Neurologie, Hopitaux de Lyon, Lyon, France
Borgess Research Institute, Lansing, Michigan
Department of Neurosurgery, University of Cincinnati, Cincinnati, Ohio
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J. W. Norris Extracranial Arterial Dissection: Anticoagulation Is the Treatment of Choice: For Stroke, September 1, 2005; 36(9): 2041 - 2042. [Full Text] [PDF] |
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