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(Stroke. 2000;31:791.)
© 2000 American Heart Association, Inc.


Letters to the Editor

Surgery for Intracerebral Hemorrhage

Barbara A. Gregson, PhD; A. David Mendelow, PhD, FRCSEd; Helen Fernandes, FRCS; A. Jane Pearson, PhD M. Shahid Siddique, FRCS

STICH, Department of Neurosurgery, University of Newcastle upon Tyne, Newcastle upon Tyne, UK

To the Editor:

We were pleased to see the report of the randomized feasibility study of early surgical treatment for supratentorial intracerebral hemorrhage by Zuccarello et al.1

This study provides yet more evidence of the need for a large randomized trial of surgery for spontaneous intracerebral hemorrhage, as has been shown previously.2 3 4 5 6 7 8 We wish to inform your readers of the progress of such a trial. The STICH (Surgical Trial in Intracerebral Haemorrhage) has been funded by the Medical Research Council (UK) but is open to centers from any country, and we would invite interested centers to contact us.

STICH is a multicenter, pragmatic, randomized trial aiming to recruit 1000 patients. The trial is managed by a team at Newcastle University (UK). To date, we have 68 centers from the United Kingdom, Germany, Sweden, Spain, Hungary, Poland, Czech Republic, Italy, Belgium, Greece, Ukraine, Russia, South Africa, Hong Kong and the United States. Randomization is performed by telephoning the Randomisation Service at Oxford University (UK) after identifying a patient, gaining consent, and completing a randomization form. An additional form is completed 2 weeks later (or at death or discharge if earlier) to record patient status at this point and details of any surgery or adverse events. Follow-up at 6 months is obtained by the team in Newcastle, who send a questionnaire to each patient for completion.

So far we have recruited 273 patients to the study, and complete 6-month follow-up data has been achieved for 130 patients. The trial is being carried . . . [Full Text of this Article]

Joseph Broderick, MD

Department of Neurology, University of Cincinnati, Cincinnati, Ohio

Thomas Brott, MD

Department of Neurology, Mayo Clinic, Jacksonville, Florida

Laurent Derex, MD

Service de Neurologie, Hopitaux de Lyon, Lyon, France

Rashmi Kothari, MD

Borgess Research Institute, Lansing, Michigan

Mario Zuccarello, MD

Department of Neurosurgery, University of Cincinnati, Cincinnati, Ohio




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