(Stroke. 2000;31:1646.)
© 2000 American Heart Association, Inc.
Original Contributions |
Assessment of Lacunar Hemorrhage Associated With Hypertensive Stroke by Echo-Planar Gradient-Echo T2*-Weighted MRI
From the Department of Radiology, Research Institute of Brain and Blood Vessels-Akita, Akita, Japan (T.K., T.O., J.H.), and the Department of Radiology, Tottori University, Faculty of Medicine, Yonago, Japan (T.K., T.O.).
Correspondence to Toshibumi Kinoshita, MD, Department of Radiology, Tottori University, Faculty of Medicine, 36-1 Nishi-cho, Yonago 683-8504, Japan. E-mail kino{at}grape.med.tottori-u.ac.jp
Background and Purpose—Echo-planar gradient-echo T2*-weighted MR imaging (GRE-EPI) may detect hypointense lesions representing microhemorrhages with high sensitivity. The aim of this study was to evaluate the effectiveness of GRE-EPI for detecting old lacunar hemorrhages in hypertensive patients with stroke.
Methods—GRE-EPI was performed with a 1.5-T MRI system in 198 hypertensive patients with stroke (130 patients with hemorrhagic stroke and 68 patients with multiple lacunar stroke) and 66 age-matched healthy elderly individuals.
Results—Concomitant hypointense foci were found in 84 (66%) patients with hemorrhagic stroke, 46 (68%) patients with multiple lacunar stroke, and 3 (5%) healthy elderly individuals. These hypointense foci were noted in the lentiform nucleus in 61 (47%) patients with hemorrhagic stroke, in the caudate nucleus in 9 (7%) patients, in the thalamus in 54 (42%) patients, in the corticosubcortical region in 57 (44%) patients, in the brain stem in 40 (34%) patients, and in the cerebellum in 32 (25%) patients.
Conclusions—GRE-EPI is effective for the detection of lacunar hemorrhages induced by hypertension.
Key Words: cerebral hemorrhage • echo-planar imaging • hypertension • lacunar infarction • magnetic resonance imaging
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