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(Stroke. 2001;32:1234.)
© 2001 American Heart Association, Inc.

Letters to the Editor

Proinflammatory Cytokines and Glutamate in Acute Stroke

Hanne Christensen, MD

University of Copenhagen, Copenhagen, Denmark

To the Editor:

I have with great interest read the article, "Proinflammatory Cytokines and Early Neurological Worsening in Ischemic Stroke," by Vila et al.¹ Bearing in mind the complexities of interleukin (IL)-6 effects, I would like to ask the authors the following questions:

Are the patients included in this study the same patients as in the earlier published studies² from the same research group concerning glutamate?

If so, is there a relationship between IL-6 and glutamate that can be identified in the material?

References

1. Vila N, Castillo J, Dávalos A, Chamorro A. Proinflammatory cytokines and early neurological worsening in ischemic stroke. Stroke. 2000;31:2325–2329.[Abstract/Free Full Text]

2. Castillo J, Dávalos A, Noya M. Progression of ischaemic stroke and excitotoxic aminoacids. Lancet. 1997;349:79–83.[Medline] [Order article via Infotrieve]

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