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(Stroke. 2002;33:1280.)
© 2002 American Heart Association, Inc.

Original Contributions

Magnetic Resonance Angiography in Childhood Arterial Brain Infarcts

A Comparative Study With Contrast Angiography

Béatrice Husson, MD; Georges Rodesch, MD; Pierre Lasjaunias, MD, PhD; Marc Tardieu, MD, PhD Guillaume Sébire, MD, PhD

From the Service de Radiologie (B.H.), Service de Neurologie, Département de Pédiatrie (M.T.), and Service de Neuroradiologie (G.R., P.L.), Hôpital Bicêtre, Université Paris XI, Le Kremlin Bicêtre, France; and Service de Neurologie Pédiatrique, Unité de Neurologie et du Développement, Cliniques universitaires Saint Luc, Université Catholique de Louvain, Brussels, Belgium (G.S.).

Correspondce to Béatrice Husson, MD, Service de Radiopédiatrie, Centre Hospitalier Universitaire de Bicêtre, 78 rue du Général Leclerc, 94275 Le Kremlin Bicêtre Cédex, France. E-mail beatrice.husson{at}bct.ap-hop-paris.fr

Background and Purpose— Contrast angiography (CA) is the reference examination for the diagnosis of cerebral arterial abnormality, but this procedure is invasive. In childhood, ischemic strokes are being increasingly investigated by means of MRI, including MR angiography (MRA). Very few data are available about the accuracy of MRA compared with CA in the specific context of acute pediatric stroke. We sought to compare the results of MRA with those of CA for the study of cerebral arteries in children with arterial infarction in an arterial distribution.

Methods— Twenty-four children presenting with 26 infarcts were studied. All were examined with cerebral MRI and MRA and with CA. The interval between CA and MRA was <3 days for most of the patients.

Results— Arterial lesions were detected in all but 2 children. They were located in the major cerebral arteries, predominantly in the anterior circulation (85% of cases). All lesions shown by CA were present on MRA (19 cases). Patients with no lesion on MRA had normal CA (2 cases). Associated distal vascular lesions and degree of arterial stenosis were more accurately detected with CA.

Conclusions— MRA is sensitive enough to provide an adequate initial evaluation of arterial brain disease in childhood.

Key Words: angiography • child • magnetic resonance angiography • stroke

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