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(Stroke. 2002;33:1522.)
© 2002 American Heart Association, Inc.

Original Contributions

High-Resolution, Contrast-Enhanced Magnetic Resonance Angiography With Elliptical Centric k-Space Ordering of Supra-aortic Arteries Compared With Selective X-Ray Angiography

Ralf Wutke, MD; Werner Lang, MD; Claudia Fellner, PhD; Rolf Janka, MD; Christan Denzel, MD; Michael Lell, MD; Werner Bautz, MD Franz A. Fellner, MD

From the Institute of Diagnostic Radiology (R.W., R.J., M.L., W.B., F.A.F.); Vascular Surgery, Department of Surgery (W.L., C.D.); and Institute of Medical Physics (C.F.), Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.

Correspondence to Ralf Wutke, MD, Institute of Diagnostic Radiology, Maximiliansplatz 1, D-91054 Erlangen, Germany. E-mail ralf.wutke{at}idr.imed.uni-erlangen.de

Background and Purpose— The objective of this study was to evaluate the relative value of high-resolution, contrast-enhanced MR angiography (CE MRA) with elliptical centric k-space ordering compared with intra-arterial x-ray angiography for imaging carotid stenosis.

Methods— Thirty patients with suspected stenosis of the carotid arteries were examined with CE MRA (1.5-T scanner) and x-ray angiography (aortic arch survey and selective imaging of both common carotid arteries). For the first time, not only the extracranial carotid bifurcation but all the vessel segments from the aortic arch to the circle of Willis were assessed by independent investigators.

Results— For the internal carotid artery in the region of the extracranial carotid bifurcation, there was a very close correlation between CE MRA and x-ray angiography (sensitivity, 100%; specificity, 92%). The initially suspected overestimation of stenosis on CE MRA in 3 cases was ultimately revealed to be an underestimation on x-ray angiography. CE MRA showed slightly poorer imaging of the basal vessel segments at the level of the aortic arch (because of breathing artifacts) and the intracranial vessel segments (because of small vessel caliber and venous superimposition due to delayed sequence starts).

Conclusions— The MRA technique described here provides reliable results in the diagnosis of carotid stenosis and is thus suitable for replacing the invasive conventional x-ray angiography method in most cases. Further technical developments with regard to spatial resolution are still required for improved visualization of small vessels (terminal carotid branches and intracranial vessels).

Key Words: carotid stenosis • contrast media • magnetic resonance angiography • magnetic resonance imaging

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