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(Stroke. 2004;35:770.)
© 2004 American Heart Association, Inc.

Original Contributions

Estimating the Cost-Effectiveness of Stroke Units in France Compared With Conventional Care

R. Launois, PhD; M. Giroud, MD; A.C. Mégnigbêto, PharmD; K. Le Lay, MBA; G. Présenté, MA; M.H. Mahagne, MD; I. Durand, MSc A.F. Gaudin, PharmD

From Réseau d’Evaluation en Economie de la Santé, Paris (R.L., A.C.M., K.L., G.P.); Université de Paris XIII, Paris (R.L.); Centre Hospitalier Universitaire, Service de Neurologie, Dijon (M.G.); Centre Hospitalier Universitaire de Nice, Nice (M.H.M.); and Laboratoire GlaxoSmithKline, Marly le Roi (I.D., A.F.G.), France.

Correspondence to Professor Robert Launois, REES France, 28 Rue d’Assas, 75006 Paris, France. E-mail launois.reesfrance{at}wanadoo.fr

Background and Purpose— The incidence of stroke in France is estimated at between 120 000 and 150 000 cases per year. This modeling study assessed the clinical and economic benefits of establishing specialized stroke units compared with conventional care.

Methods— Data from the Dijon stroke registry were used to determine healthcare trajectories according to the degree of autonomy and organization of patient care. The relative risks of death or institutionalization or death or dependence after passage through a stroke unit were compared with conventional care. These risks were then inserted with the costing data into a Markov model to estimate the cost-effectiveness of stroke units.

Results— Patients cared for in a stroke unit survive more trimesters without sequelae in the 5 years after hospitalization than those cared for conventionally (11.6 versus 8.28 trimesters). The mean cost per patient at 5 years was estimated at 30 983 for conventional care and 34 638 in a stroke unit. An incremental cost-effectiveness ratio for stroke units of 1359 per year of life gained without disability was estimated.

Conclusions— The cost-effectiveness ratio for stroke units is much lower than the threshold (53 400 ) of acceptability recognized by the international scientific community. This finding justifies organizational changes in the management of stroke patients and the establishment of stroke units in France.

Key Words: cost-benefit analysis • economics • Markov chains • stroke • stroke units

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