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Stroke. 2006;37:577-617
doi: 10.1161/01.STR.0000199147.30016.74
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(Stroke. 2006;37:577.)
© 2006 American Heart Association, Inc.


AHA/ASA Guidelines

Guidelines for Prevention of Stroke in Patients With Ischemic Stroke or Transient Ischemic Attack

A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association Council on Stroke: Co-Sponsored by the Council on Cardiovascular Radiology and Intervention: The American Academy of Neurology affirms the value of this guideline.

Ralph L. Sacco, MD, MS, FAHA, FAAN, Chair; Robert Adams, MD, FAHA, Vice Chair; Greg Albers, MD; Mark J. Alberts, MD, FAHA; Oscar Benavente, MD; Karen Furie, MD, MPH, FAHA; Larry B. Goldstein, MD, FAHA, FAAN; Philip Gorelick, MD, MPH, FAHA, FAAN; Jonathan Halperin, MD, FAHA; Robert Harbaugh, MD, FACS, FAHA; S. Claiborne Johnston, MD, PhD; Irene Katzan, MD, FAHA; Margaret Kelly-Hayes, RN, EdD, FAHA; Edgar J. Kenton, MD, FAHA, FAAN; Michael Marks, MD; Lee H. Schwamm, MD, FAHA Thomas Tomsick, MD, FAHA
Abstract

The aim of this new statement is to provide comprehensive and timely evidence-based recommendations on the prevention of ischemic stroke among survivors of ischemic stroke or transient ischemic attack. Evidence-based recommendations are included for the control of risk factors, interventional approaches for atherosclerotic disease, antithrombotic treatments for cardioembolism, and the use of antiplatelet agents for noncardioembolic stroke. Further recommendations are provided for the prevention of recurrent stroke in a variety of other specific circumstances, including arterial dissections; patent foramen ovale; hyperhomocysteinemia; hypercoagulable states; sickle cell disease; cerebral venous sinus thrombosis; stroke among women, particularly with regard to pregnancy and the use of postmenopausal hormones; the use of anticoagulation after cerebral hemorrhage; and special approaches for the implementation of guidelines and their use in high-risk populations. (Stroke. 2006;37:577-617.)


Key Words: AHA Scientific Statements • ischemia • ischemia attack, transient • stroke




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Am. J. Neuroradiol.Home page
D.C. Suh, J.K. Kim, J.W. Choi, B.S. Choi, H.W. Pyun, Y.J. Choi, M.-H. Kim, H.R. Yang, H.I. Ha, S.J. Kim, et al.
Intracranial Stenting of Severe Symptomatic Intracranial Stenosis: Results of 100 Consecutive Patients
AJNR Am. J. Neuroradiol., April 1, 2008; 29(4): 781 - 785.
[Abstract] [Full Text] [PDF]


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StrokeHome page
P. Verro, P. B. Gorelick, and D. Nguyen
Aspirin Plus Dipyridamole Versus Aspirin for Prevention of Vascular Events After Stroke or TIA: A Meta-Analysis
Stroke, April 1, 2008; 39(4): 1358 - 1363.
[Abstract] [Full Text] [PDF]


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StrokeHome page
N. K. Hills and S. C. Johnston
Trends in Usage of Alternative Antiplatelet Therapy After Stroke and Transient Ischemic Attack
Stroke, April 1, 2008; 39(4): 1228 - 1232.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
E. Doufekias, A. Z. Segal, and J. R. Kizer
Cardiogenic and aortogenic brain embolism.
J. Am. Coll. Cardiol., March 18, 2008; 51(11): 1049 - 1059.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
E. I. Levy, J. Mocco, R. M. Samuelson, R. D. Ecker, B. S. Jahromi, and L. N. Hopkins
Optimal treatment of carotid artery disease.
J. Am. Coll. Cardiol., March 11, 2008; 51(10): 979 - 985.
[Abstract] [Full Text] [PDF]


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Am. J. Neuroradiol.Home page
A. Kastrup, K. Groschel, T. Nagele, A. Riecker, F. Schmidt, S. Schnaudigel, and U. Ernemann
Effects of Age and Symptom Status on Silent Ischemic Lesions after Carotid Stenting with and without the Use of Distal Filter Devices
AJNR Am. J. Neuroradiol., March 1, 2008; 29(3): 608 - 612.
[Abstract] [Full Text] [PDF]


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Arch Intern MedHome page
K. A. LaBresh, M. J. Reeves, M. R. Frankel, D. Albright, and L. H. Schwamm
Hospital Treatment of Patients With Ischemic Stroke or Transient Ischemic Attack Using the "Get With The Guidelines" Program
Arch Intern Med, February 25, 2008; 168(4): 411 - 417.
[Abstract] [Full Text] [PDF]


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Vasc MedHome page
M. E Schachter, H. A Tran, and S. S Anand
Oral anticoagulants and non-cardioembolic stroke prevention
Vascular Medicine, February 1, 2008; 13(1): 55 - 62.
[Abstract] [PDF]


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StrokeHome page
B. Hallstrom, A.-C. Jonsson, C. Nerbrand, B. Norrving, and A. Lindgren
Stroke Incidence and Survival in the Beginning of the 21st Century in Southern Sweden: Comparisons With the Late 20th Century and Projections Into the Future
Stroke, January 1, 2008; 39(1): 10 - 15.
[Abstract] [Full Text] [PDF]


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NeurologyHome page
A. Towfighi, J. L. Saver, R. Engelhardt, and B. Ovbiagele
A midlife stroke surge among women in the United States
Neurology, November 13, 2007; 69(20): 1898 - 1904.
[Abstract] [Full Text] [PDF]


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CirculationHome page
R. M. Samuelson, J. Yamamoto, E. I. Levy, A. H. Siddiqui, and L. N. Hopkins
The Argument to Support Broader Application of Extracranial Carotid Artery Stent Technology
Circulation, October 2, 2007; 116(14): 1602 - 1610.
[Full Text] [PDF]


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StrokeHome page
C. S. Hodgson
To FAST or Not to FAST?
Stroke, October 1, 2007; 38(10): 2631 - 2632.
[Full Text] [PDF]


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CirculationHome page
L. B. Goldstein
Acute Ischemic Stroke Treatment in 2007
Circulation, September 25, 2007; 116(13): 1504 - 1514.
[Full Text] [PDF]


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Am. J. Neuroradiol.Home page
D. Seidenwurm, P. Turski, J. Barr, J. Connors, M. Lev, S. Mukherji, and E. Russell
Performance Measures in Neuroradiology
AJNR Am. J. Neuroradiol., September 1, 2007; 28(8): 1435 - 1438.
[Abstract] [Full Text] [PDF]


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NEJMHome page
H. B. van der Worp and J. van Gijn
Acute Ischemic Stroke
N. Engl. J. Med., August 9, 2007; 357(6): 572 - 579.
[Full Text] [PDF]


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CirculationHome page
T. L. P. Slottow, D. H. Steinberg, and R. Waksman
Overview of the 2007 Food and Drug Administration Circulatory System Devices Panel Meeting on Patent Foramen Ovale Closure Devices
Circulation, August 7, 2007; 116(6): 677 - 682.
[Abstract] [Full Text] [PDF]


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StrokeHome page
B. Norrving, P. Wester, K. S. Sunnerhagen, A. Terent, A. Sohlberg, F. Berggren, P.-O. Wester, K. Asplund, for the Stroke Guidelines Working Group,, and National Board of Health and Welfare, Stockholm, S
Beyond Conventional Stroke Guidelines: Setting Priorities
Stroke, July 1, 2007; 38(7): 2185 - 2190.
[Abstract] [Full Text] [PDF]


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StrokeHome page
M. S. Dhamoon, W. Tai, B. Boden-Albala, T. Rundek, M. C. Paik, R. L. Sacco, and M. S.V. Elkind
Risk of Myocardial Infarction or Vascular Death After First Ischemic Stroke: The Northern Manhattan Study
Stroke, June 1, 2007; 38(6): 1752 - 1758.
[Abstract] [Full Text] [PDF]


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StrokeHome page
R. L. Sacco
The 2006 William Feinberg Lecture: Shifting the Paradigm From Stroke to Global Vascular Risk Estimation
Stroke, June 1, 2007; 38(6): 1980 - 1987.
[Abstract] [Full Text] [PDF]


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StrokeHome page
G. Saposnik and M. K. Kapral
Poststroke Care: Chronicles of a Neglected Battle
Stroke, June 1, 2007; 38(6): 1727 - 1729.
[Full Text] [PDF]


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Rheumatology (Oxford)Home page
C. Christodoulou, S. Sangle, and D. P. D'Cruz
Vasculopathy and arterial stenotic lesions in the antiphospholipid syndrome
Rheumatology, June 1, 2007; 46(6): 907 - 910.
[Abstract] [Full Text] [PDF]


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CirculationHome page
H. P. Adams Jr, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, et al.
Guidelines for the Early Management of Adults With Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists.
Circulation, May 22, 2007; 115(20): e478 - e534.
[Abstract] [Full Text] [PDF]


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Arch NeurolHome page
J. A. Viehman, J. L. Saver, D. S. Liebeskind, S. Starkman, L. K. Ali, B. Buck, T. Razinia, and B. Ovbiagele
Utility of Urinalysis in Discriminating Cardioembolic Stroke Mechanism
Arch Neurol, May 1, 2007; 64(5): 667 - 670.
[Abstract] [Full Text] [PDF]


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Mayo Clin Proc.Home page
G. E. Kikano and M. T. Brown
Antiplatelet Therapy for Atherothrombotic Disease: An Update for the Primary Care Physician
Mayo Clin. Proc., May 1, 2007; 82(5): 583 - 593.
[Abstract] [Full Text] [PDF]


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StrokeHome page
A. Kastrup, K. Groschel, and U. Ernemann
Response to Letter by Cohen
Stroke, May 1, 2007; 38(5): e19 - e20.
[Full Text] [PDF]


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StrokeHome page
L. H. Kuller
So, What's New?
Stroke, May 1, 2007; 38(5): 1427 - 1429.
[Full Text] [PDF]


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StrokeHome page
P. B. Gorelick
Combining Aspirin With Oral Anticoagulant Therapy: Is This a Safe and Effective Practice in Patients With Atrial Fibrillation?
Stroke, May 1, 2007; 38(5): 1652 - 1654.
[Full Text] [PDF]


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StrokeHome page
H. P. Adams Jr, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, et al.
Guidelines for the Early Management of Adults With Ischemic Stroke: A Guideline From the American Heart Association/ American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists
Stroke, May 1, 2007; 38(5): 1655 - 1711.
[Abstract] [Full Text] [PDF]


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Journal of Pharmacy PracticeHome page
S. C. Fagan, H. F. Elewa, and D. J. Rychly
Statin Therapy for Secondary Stroke Prevention: Evidence Catches Up to Practice
Journal of Pharmacy Practice, April 1, 2007; 20(2): 117 - 122.
[Abstract] [PDF]


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StrokeHome page
M. Moussouttas
Emerging Therapies: ESPRIT
Stroke, April 1, 2007; 38(4): 1142 - 1142.
[Full Text] [PDF]


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CirculationHome page
J. K. Liao
Secondary Prevention of Stroke and Transient Ischemic Attack: Is More Platelet Inhibition the Answer?
Circulation, March 27, 2007; 115(12): 1615 - 1621.
[Abstract] [Full Text] [PDF]