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(Stroke. 2009;40:321.)
© 2009 American Heart Association, Inc.

Research Letters

Intracranial Aneurysms Coiling With Matrix

Immediate Results in 152 Patients and Midterm Anatomic Follow-Up From 115 Patients

Michel Piotin, MD, PhD; Laurent Spelle, MD, PhD; Charbel Mounayer, MD; Carolina Loureiros, MD; Askar Ghorbani, MD Jacques Moret, MD

From the Department of Interventional and Functional Neuroradiology, Foundation Rothschild Hospital, Paris, France.

Correspondence to Jacques Moret, MD, Service de Neuroradiologie Interventionnelle et Fonctionnelle, Hôpital de la Fondation Ophtalmologique Adolphe de Rothschild, 25–29 rue Manin 75940 Paris, Cedex 19, France. E-mail jmoret{at}fo-rothschild.fr

Background and Purpose— We report our experience using Matrix coils in coiling of cerebral aneurysms.

Methods— Clinical and angiographic outcomes of 152 patients (165 aneurysms) treated exclusively with Matrix coils were retrospectively analyzed.

Results— There were 74 ruptured aneurysms (44.8%) and 91 unruptured (55.2%). After coiling, 84 (50.9%) aneurysms were occluded, 38 (23.0%) aneurysms had a neck remnant, and 43 (26.1%) aneurysms had a sac remnant. Packing ranged from 10% to 49% (mean and median, 27%). Overall treatment-induced morbidity was 6.6% and mortality was 1.3% (10 of 152 to 2 of 152, respectively). One hundred fifteen (69.7%) aneurysms were followed, disclosing 42 (36.5%) recurrences at a mean period of 9 months (median, 6 months; range, 1 to 28 months). The recurrence rate for small aneurysms (<10 mm) was 28 (31.1%) of 90, whereas for larger aneurysms (10 mm), the recurrence rate was 14 (56.0%) of 25 (P=0.0336). When packing was 25%, the recurrence rate was 44.4%, whereas for aneurysms with packing >25%, the recurrence rate was 29.8% (P=0.1588). Recurrence rate was not correlated to packing. Ruptured aneurysms recurred more frequently than unruptured aneurysms (P=0.0004).

Conclusion— Matrix coils provided no better recanalization rates than those reported previously for bare platinum coils.

Key Words: cerebral aneurysm • embolization • therapeutic