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(Stroke. 2009;40:S126.)
© 2009 American Heart Association, Inc.

Neuroprotection

Multimodal Neuroprotective Therapy With Induced Hypothermia After Ischemic Stroke

From the Department of Neuroscience (T.M.H., P.D.L.), University of California, San Diego, San Diego, Calif; and the Department of Veterans’ Affairs San Diego (P.D.L.), San Diego, Calif.

Correspondence to Thomas M. Hemmen, MD, PhD, Department of Neuroscience, University of California, San Diego, 200 West Arbor Drive, MC 8466, OPC 3rd Floor, Suite 3, San Diego, CA 92103-8466. E-mail themmen{at}ucsd.edu

Neuroprotective therapies have so far failed to provide improved neurological function and outcome after stroke. A recent focus on multimodal therapies, including the combination of neuroprotective medications with hypothermia, opens a promising new treatment strategy. Advances in hypothermia administration make it one of the most promising neuroprotective therapies available and an ideal candidate for combination with other neuroprotective approaches.

Key Words: hypothermia • ischemia • neuroprotection