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(Stroke. 1974;5:207.)
© 1974 American Heart Association, Inc.

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Regional Cerebral Blood Flow in Patients With Hypertensive Intracerebral Hemorrhage

HIROSHI KAWAKAMI M.D.¹; TAKASHI KUTSUZAWA M.D.¹; KAZUO UEMURA M.D.¹; YOSHIHARU SAKURAI M.D.¹; TAKASHI NAKAMURA M.D.¹

¹ Divisions of Internal Medicine, Radiology and Neurosurgery, the Research Institute of Brain and Blood Vessels, 6-10, Senshu-Kubota-Machi, Akita, Japan

Regional cerebral blood flow was measured by ¹³³Xe clearance method in 44 patients with hypertensive intracerebral hemorrhage (HIH) within three weeks from attack. Mean CBF in cases with the more disturbed consciousness was the lower value. There was no definite relationship between mean CBF and the duration from last stroke to measurement. In 44 cases, 35 showed hematoma of so-called "lateral type" and nine showed a "mesial type." There was no difference of mean CBF between these two groups. In the group with lateral-type hematoma, 14 cases were thought to show large space-occupying signs, and their mean CBF was significantly lower than that of the other 21 cases.

In 16 cases, relative hyperemic regions were observed in both the focal and nonfocal areas. In seven cases, relative ischemic regions were frequently in nonfocus rather than focus.

Response of hyperemic region to carbon dioxide was good in seven and poor in three regions in focal area, and was good in eight and poor in one region in nonfocal area. Reactivity of ischemic region to 5% CO₂ inhalation was good in three and poor in zero regions in focus, and was good in three and poor in two regions in nonfocus.

Early venous filling (EVF) was observed in 13 cases and all of them were with lateral-type hematomas.

Only four out of 13 cases showed good correlation between angiographical findings and cerebral circulation.

Key Words: ¹³³Xe clearance method • cerebrovascular diseases • CO₂ response • early venous filling

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