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Published Online
on October 4, 2007

Stroke. 2007
Published online before print October 4, 2007, doi: 10.1161/STROKEAHA.107.484139
A more recent version of this article appeared on November 1, 2007
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Submitted on February 3, 2007
Revised on May 2, 2007
Accepted on May 3, 2007

Stroke Incidence, Prognosis, 30-Day, and 1-Year Case Fatality Rates in Matão, Brazil. A Population-Based Prospective Study

Cesar Minelli MD, PhD*; Lee Fu Fen MD; and Denise P. Camara Minelli RN

From Department of Neurology (C.M., L.F.F., D.P.C.M.), Hospital Carlos Fernando Malzoni, Matão, São Paulo, Brazil.

* To whom correspondence should be addressed. E-mail: cminelli{at}netsite.com.br.

Background and Purpose—Stroke is the main cause of death in Brazil and no prospective population-based study has been conducted in the country. The purpose of this study was to determine the incidence of stroke, stroke subtypes, case fatality, and prognosis after 1 year of follow-up in the city of Matão, Brazil.

Methods—Using overlapping methods of case ascertainment, all stroke cases that occurred in the city of Matão (population, 75 053) from November 1, 2003 to October 31, 2004 were followed-up at 1 month and 1 year after the episode. Standard criteria for population-based stroke studies were followed.

Results—Of 141 suspect stroke cases identified, 81 were first-ever-in-a-lifetime strokes. All patients underwent a CT scan. The crude annual incidence rate per 100 000 per year was 108 (95% CI, 85.7–134.1) and the rate adjusted for sex and age to the Segi population was 137 (95% CI, 112.0 to 166.4) per 100 000 inhabitants per year. Ischemic stroke occurred in 69 (85.2%) subjects, intracerebral hemorrhage in 11 (13.6%), and subarachnoid hemorrhage in 1 (1.2%). The 30-day case fatality rate was 18.5 and the 1-year case fatality rate was 30.9%. After 1 year of follow-up, 43% of the patients were independent in activities of daily living, 49.4% had independent gait, and 15.9% had a recurrent stroke.

Conclusions—The present results are similar to those obtained in other stroke population-based studies. Future studies in Matão will provide the opportunity to discover ways to decrease the stroke burden in Brazil.


Key words: epidemiology • incidence • outcome • stroke




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