Published Online
on July 26, 2007

A more recent version of this article appeared on September 1, 2007

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Submitted on February 5, 2007
Accepted on March 1, 2007

South Asian Patients With Ischemic Stroke. Intracranial Large Arteries Are the Predominant Site of Disease

Deidre A. De Silva MRCP^*; Fung-Peng Woon MSc; Moi-Pin Lee RBT; Christopher P.L.H. Chen FRCP; Hui-Meng Chang MBBS, FAMS; and Meng-Cheong Wong MBBS, FRCP

From the National Neuroscience Institute (D.A.D., H.M.C., M.C.W.), Singapore General Hospital Campus, Singapore; the National Heart Centre (F.P.W.), Singapore; Singapore General Hospital (M.P.L.), Singapore; and the National University of Singapore (C.P.L.H.C.), Singapore.

^* To whom correspondence should be addressed. E-mail: gnrdsd{at}sgh.com.sg.

Background and Purpose—South Asians are the most prevalent ethnic group in the world. Intracranial disease is the most common vascular lesion worldwide.

Methods—We prospectively studied 200 consecutive ethnic South Asian patients with acute ischemic stroke in Singapore.

Results—Intracranial large-artery disease was prevalent among 54% of all stroke subtypes and was independently associated with hypertension and higher serum erythrocyte sedimentation rate.

Conclusions—Among ethnic South Asian patients with ischemic stroke, intracranial large arteries are the predominant site of disease.

Key words: hypertension • inflammation • intracranial • ischemic stroke • South Asian

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