Published Online
on August 23, 2007

A more recent version of this article appeared on October 1, 2007

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Submitted on March 24, 2007
Accepted on April 12, 2007

Endovascular Occlusion of Aneurysms Using a New Bioactive Coil. A Matched Pair Analysis With Bare Platinum Coils

Martin Bendszus MD^*; Andreas J. Bartsch MD; and Laszlo Solymosi MD

From the Department of Neuroradiology, University of Würzburg, Germany.

^* To whom correspondence should be addressed. E-mail: bendszus{at}neuroradiologie.uni-wuerzburg.de.

Background and Purpose—To assess safety and efficacy data of a new bioactive coil (Cerecyte) which is loaded with polyglycolic acid on the inside of the coil.

Methods—Fifty-four patients harboring 55 aneurysms were treated with Cerecyte coils. These aneurysms were matched in localization and size with aneurysms treated with bare platinum coils.

Results—Periprocedural complications and handling did not differ between both groups. Initial aneurysm occlusion was comparable in both treatment groups. At 6 months angiographic follow-up, the aneurysms occluded with Cerecyte coils had a higher chance for complete occlusion (P=0.045) and tended to a lower retreatment rate (P=0.056).

Conclusions—Cerecyte coils are as safe as bare platinum coils in the endovascular occlusion of aneurysms. This matched pair analysis indicates a higher occlusion rate of aneurysms occluded with Cerecyte coils.

Key words: aneurysm • bioactive • coil • endovascular

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