on November 21, 2007
Published online before print November 21, 2007, doi: 10.1161/STROKEAHA.107.493320
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Submitted on May 11, 2007
From the Gardiner Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK. * To whom correspondence should be addressed. E-mail: Tjq1t{at}clinmed.gla.ac.uk.
Background and Purpose—Stroke outcome assessment requires some measure of functional recovery. Several instruments are in common use but all have recognized limitations. We examined duration of stay in the patient’s own home over the first 90 days since stroke—"home-time"—as an alternative outcome likely to show graded response with improved reliability. Methods—We examined prospectively collected data from the GAIN International trial using analysis of variance with Bonferroni contrasts of adjacent modified Rankin scale score categories. Results—We had full outcome data from 1717 of 1788 patients. Increasing home-time was associated with improved modified Rankin scale scores (P<0.0001). The relationship held across all modified Rankin scale grades except 4 to 5. Conclusions—Home-time offers a robust, useful, and easily validated outcome measure for stroke, particularly across better recovery levels.
Revised on June 6, 2007
Accepted on June 7, 2007
Time Spent at Home Poststroke. "Home-Time" a Meaningful and Robust Outcome Measure for Stroke Trials
Terence J. Quinn MRCP*;
Key words: cerebrovascular accident • health economics • modified Rankin scale score • outcome assessment • stroke treatment
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